Until recently, radiation effects have been considered to be mainly due to nuclear DNA
damage and their management by repair mechanisms. However, molecular biology studies …

Cellular exposure to ionizing radiation leads to oxidizing events that alter atomic structure
through direct interactions of radiation with target macromolecules or via products of water …

Background Radiotherapy outcomes are limited by toxicity in the healthy tissues
surrounding the irradiated tumor. Recent pre-clinical studies have shown that irradiations …

The disability, mortality and costs due to ionizing radiation (IR)-induced osteoporotic bone
fractures are substantial and no effective therapy exists. Ionizing radiation increases cellular …

Ionizing radiation (IR) has found widespread application in modern medicine, including
medical imaging and radiotherapy. As a result, both patients and healthcare professionals …

Despite years of research, understanding of the space radiation environment and the risk it
poses to long-duration astronauts remains limited. There is a disparity between research …

Non-DNA targeted effects of ionising radiation, which include genomic instability, and a
variety of bystander effects including abscopal effects and bystander mediated adaptive …

Radiotherapy is an essential and effective treatment modality for cancer. Excessive levels of
reactive oxygen species (ROS) induced by ionizing radiation disrupt the redox homeostasis …

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are formed as a result
of natural cellular processes, intracellular signaling, or as adverse responses associated …

Non-targeted effects (NTE) have been generally regarded as a low-dose ionizing radiation
(IR) phenomenon. Recently, regarding long distant abscopal effects have also been …