The search for better treatment strategies for mansonellosis: an expert perspective

MU Ferreira, JL Crainey, FG Gobbi - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Four species of the Mansonella genus infect millions of people across sub-
Saharan Africa and Central and South America. Most infections are asymptomatic, but …

Multiple Lineages of Nematode-Wolbachia Symbiosis in Supergroup F and Convergent Loss of Bacterioferritin in Filarial Wolbachia

A Sinha, Z Li, CB Poole, L Ettwiller… - Genome Biology and …, 2023 - academic.oup.com
The intracellular endosymbiotic proteobacteria Wolbachia have evolved across the phyla
nematoda and arthropoda. In Wolbachia phylogeny, supergroup F is the only clade known …

[HTML][HTML] Distinct loiasis infection states and associated clinical and hematological manifestations in patients from Gabon

L Veletzky, KA Eberhardt, J Hergeth… - Plos Neglected …, 2022 - journals.plos.org
Background Loiasis–a filarial disease endemic in Central and West Africa–is increasingly
recognized as significant individual and public health concern. While the understanding of …

[HTML][HTML] Genomes of the human filarial parasites Mansonella perstans and Mansonella ozzardi

A Sinha, Z Li, CB Poole, RD Morgan… - Frontiers in Tropical …, 2023 - frontiersin.org
The filarial parasites Mansonella ozzardi and Mansonella perstans, causative agents of
mansonellosis, infect hundreds of millions of people worldwide, yet remain among the most …

[HTML][HTML] Whole genome analysis of two sympatric human Mansonella: Mansonella perstans and Mansonella sp “DEUX”

M Rodi, C Gross, TL Sandri, L Berner… - Frontiers in Cellular …, 2023 - frontiersin.org
Mansonella species are filarial parasites that infect humans worldwide. Although these
infections are common, knowledge of the pathology and diversity of the causative species is …

[HTML][HTML] Efficacy, safety, and tolerability of albendazole and ivermectin based regimens for the treatment of microfilaraemic loiasis in adult patients in Gabon: A …

R Zoleko-Manego, R Kreuzmair… - Plos Neglected …, 2023 - journals.plos.org
Background There is a lack of systematic evidence for strategies to control loiasis
transmission in highly endemic regions. Here we assessed albendazole and ivermectin …

A large case series of travel-related Mansonella perstans (vector-borne filarial nematode): a TropNet study in Europe

F Tamarozzi, P Rodari, J Salas-Coronas… - Journal of Travel …, 2022 - academic.oup.com
Abstract Background Infection with Mansonella perstans is a neglected filariasis, widely
distributed in sub-Saharan Africa, characterized by an elusive clinical picture; treatment for …

[HTML][HTML] Characterising co-infections with Plasmodium spp., Mansonella perstans or Loa loa in asymptomatic children, adults and elderly people living on Bioko …

CA Yoboue, S Hosch, OT Donfack… - PLOS Neglected …, 2022 - journals.plos.org
Background Regular and comprehensive epidemiological surveys of the filarial nematodes
Mansonella perstans and Loa loa in children, adolescents and adults living across Bioko …

[HTML][HTML] Analysis of diagnostic test outcomes in a large loiasis cohort from an endemic region: Serological tests are often false negative in hyper-microfilaremic …

L Veletzky, KA Eberhardt, J Hergeth… - PLOS Neglected …, 2024 - journals.plos.org
Background The parasitic disease loiasis is associated with significant morbidity and
mortality. Individuals with hyper-microfilaremia (greater than 20,000 microfilariae per mL of …

[HTML][HTML] Very low prevalence of Mansonella perstans -specific cell-free DNA in serum samples of Ghanaian HIV patients

KA Eberhardt, L Veletzky, F Weinreich… - European Journal of …, 2023 - akjournals.com
Background Mansonellosis is a widely neglected helminth disease which is predominantly
observed in tropical regions. This study was conducted to assess potential associations of …