Regulatory mechanisms of cytoneme-based morphogen transport

CA Daly, ET Hall, SK Ogden - Cellular and Molecular Life Sciences, 2022 - Springer
During development and tissue homeostasis, cells must communicate with their neighbors
to ensure coordinated responses to instructional cues. Cues such as morphogens and …

Extracellular vesicles and membrane protrusions in developmental signaling

CM Gustafson, LS Gammill - Journal of Developmental Biology, 2022 - mdpi.com
During embryonic development, cells communicate with each other to determine cell fate,
guide migration, and shape morphogenesis. While the relevant secreted factors and their …

Filopodia rotate and coil by actively generating twist in their actin shaft

N Leijnse, YF Barooji, MR Arastoo, SL Sønder… - Nature …, 2022 - nature.com
Filopodia are actin-rich structures, present on the surface of eukaryotic cells. These
structures play a pivotal role by allowing cells to explore their environment, generate …

[HTML][HTML] A macrophage subpopulation promotes airineme-mediated intercellular communication in a matrix metalloproteinase-9 dependent manner

RL Bowman, D Wang, DS Eom - Cell reports, 2023 - cell.com
Tissue-resident macrophages are heterogeneous and perform location-dependent
functions. Skin resident macrophages play intriguing roles in long-distance intercellular …

Zebrafish airinemes optimize their shape between ballistic and diffusive search

S Park, H Kim, Y Wang, DS Eom, J Allard - Elife, 2022 - elifesciences.org
In addition to diffusive signals, cells in tissue also communicate via long, thin cellular
protrusions, such as airinemes in zebrafish. Before establishing communication, cellular …

HvRNASET2 Regulate Connective Tissue and Collagen I Remodeling During Wound Healing Process

N Baranzini, L Pulze, G Tettamanti, F Acquati… - Frontiers in …, 2021 - frontiersin.org
Several studies have recently demonstrated that the correct regeneration of damaged
tissues and the maintaining of homeostasis after wounds or injuries are tightly connected to …

Cytoneme-mediated intercellular signaling in keratinocytes essential for epidermal remodeling

Y Wang, Q He, O Has, K Forouzesh, DS Eom - bioRxiv, 2023 - biorxiv.org
The skin, the body's largest organ, functions as a primary defense mechanism. Epidermal
stem cells supply undifferentiated keratinocytes that differentiate as they migrate toward the …

[HTML][HTML] CD44 facilitates adhesive interactions in airineme-mediated intercellular signaling

RL Bowman, J Kim, DS Eom - bioRxiv, 2024 - ncbi.nlm.nih.gov
Specialized cellular protrusions facilitate local intercellular communications in various
species, including mammals. Among these, airinemes play a crucial role in pigment pattern …

Airineme-Mediated Intercellular Communication

DS Eom - … and Interorganellar Transfer and Communication in …, 2024 - Springer
Intercellular communication is indispensable across multicellular organisms, and any
aberration in this process can give rise to significant anomalies in developmental and …

Interleukin-17 regulates epidermal remodeling via keratinocyte cytonemes.

Y Wang, Q He, O Has, K Forouzesh… - Biorxiv: the Preprint …, 2023 - europepmc.org
The skin, the largest organ in our body, serves as our primary defense mechanism.
Epidermal stem cells supply undifferentiated keratinocytes, which undergo differentiation as …