Regulatory mechanisms of cytoneme-based morphogen transport
During development and tissue homeostasis, cells must communicate with their neighbors
to ensure coordinated responses to instructional cues. Cues such as morphogens and …
to ensure coordinated responses to instructional cues. Cues such as morphogens and …
Extracellular vesicles and membrane protrusions in developmental signaling
CM Gustafson, LS Gammill - Journal of Developmental Biology, 2022 - mdpi.com
During embryonic development, cells communicate with each other to determine cell fate,
guide migration, and shape morphogenesis. While the relevant secreted factors and their …
guide migration, and shape morphogenesis. While the relevant secreted factors and their …
Filopodia rotate and coil by actively generating twist in their actin shaft
Filopodia are actin-rich structures, present on the surface of eukaryotic cells. These
structures play a pivotal role by allowing cells to explore their environment, generate …
structures play a pivotal role by allowing cells to explore their environment, generate …
[HTML][HTML] A macrophage subpopulation promotes airineme-mediated intercellular communication in a matrix metalloproteinase-9 dependent manner
RL Bowman, D Wang, DS Eom - Cell reports, 2023 - cell.com
Tissue-resident macrophages are heterogeneous and perform location-dependent
functions. Skin resident macrophages play intriguing roles in long-distance intercellular …
functions. Skin resident macrophages play intriguing roles in long-distance intercellular …
Zebrafish airinemes optimize their shape between ballistic and diffusive search
In addition to diffusive signals, cells in tissue also communicate via long, thin cellular
protrusions, such as airinemes in zebrafish. Before establishing communication, cellular …
protrusions, such as airinemes in zebrafish. Before establishing communication, cellular …
HvRNASET2 Regulate Connective Tissue and Collagen I Remodeling During Wound Healing Process
N Baranzini, L Pulze, G Tettamanti, F Acquati… - Frontiers in …, 2021 - frontiersin.org
Several studies have recently demonstrated that the correct regeneration of damaged
tissues and the maintaining of homeostasis after wounds or injuries are tightly connected to …
tissues and the maintaining of homeostasis after wounds or injuries are tightly connected to …
Cytoneme-mediated intercellular signaling in keratinocytes essential for epidermal remodeling
Y Wang, Q He, O Has, K Forouzesh, DS Eom - bioRxiv, 2023 - biorxiv.org
The skin, the body's largest organ, functions as a primary defense mechanism. Epidermal
stem cells supply undifferentiated keratinocytes that differentiate as they migrate toward the …
stem cells supply undifferentiated keratinocytes that differentiate as they migrate toward the …
[HTML][HTML] CD44 facilitates adhesive interactions in airineme-mediated intercellular signaling
RL Bowman, J Kim, DS Eom - bioRxiv, 2024 - ncbi.nlm.nih.gov
Specialized cellular protrusions facilitate local intercellular communications in various
species, including mammals. Among these, airinemes play a crucial role in pigment pattern …
species, including mammals. Among these, airinemes play a crucial role in pigment pattern …
Airineme-Mediated Intercellular Communication
DS Eom - … and Interorganellar Transfer and Communication in …, 2024 - Springer
Intercellular communication is indispensable across multicellular organisms, and any
aberration in this process can give rise to significant anomalies in developmental and …
aberration in this process can give rise to significant anomalies in developmental and …
Interleukin-17 regulates epidermal remodeling via keratinocyte cytonemes.
Y Wang, Q He, O Has, K Forouzesh… - Biorxiv: the Preprint …, 2023 - europepmc.org
The skin, the largest organ in our body, serves as our primary defense mechanism.
Epidermal stem cells supply undifferentiated keratinocytes, which undergo differentiation as …
Epidermal stem cells supply undifferentiated keratinocytes, which undergo differentiation as …