Prevention of Epithelial Ovarian Cancer

TA Sellers, LC Peres… - Cold Spring …, 2023 - perspectivesinmedicine.cshlp.org
Given the challenges with achieving effective and durable treatment for epithelial ovarian
cancer, primary prevention is highly desirable. Fortunately, decades of research have …

Systemic inflammation factors as survival prognosis markers in ovarian neoplasm and the relationship with cancer-associated inflammatory mediators—a review

AL Dinca, A Diaconu, RD Birla… - International …, 2023 - journals.sagepub.com
At the level of the genital system, ovarian neoplasm is the most frequent cause of morbidity
and mortality. In the specialized literature, the coexistence of an inflammatory process is …

[HTML][HTML] Nectin-4 as blood-based biomarker enables detection of early ovarian cancer stages

C Rogmans, J Feuerborn, L Treeck, N Tribian… - Cancers, 2022 - mdpi.com
Simple Summary Ovarian cancer is usually diagnosed in an advanced stage of the disease
and is associated with a poor prognosis. Therefore, it is important to find reliable biomarkers …

CXCL13 and CXCR5 are upregulated in PCOS mice ovaries but downregulated following metformin administration

A Ullah, S Pervaz, EA Adu-Gyamfi, A Czika… - Molecular and Cellular …, 2022 - Elsevier
Polycystic ovary syndrome (PCOS) is becoming a common pathology among women, yet its
pathogenesis remains enigmatic. The chemokine CXC motif ligand 13 (CXCL13) and its …

[HTML][HTML] Influences of gastrointestinal microbiota dysbiosis on serum proinflammatory markers in epithelial ovarian cancer development and progression

DE Mahoney, P Chalise, F Rahman, JD Pierce - Cancers, 2022 - mdpi.com
Simple Summary Advanced epithelial ovarian cancer (EOC) is the deadliest gynecologic
cancer due to the lack of available early screening methods that are available in clinical …

[HTML][HTML] New insights into Chlamydia pathogenesis: Role of leukemia inhibitory factor

J Wang, K Wang - Frontiers in Cellular and Infection Microbiology, 2022 - frontiersin.org
Chlamydia trachomatis (Ct) is the leading cause of bacterial sexually transmitted infections
worldwide. Since the symptoms of Ct infection are often subtle or absent, most people are …

[HTML][HTML] Pro-inflammatory Cytokines and CXC Chemokines as Game-Changer in Age-Associated Prostate Cancer and Ovarian Cancer: Insights from Preclinical and …

A Ullah, Y Chen, RK Singla, D Cao, B Shen - Pharmacological Research, 2024 - Elsevier
Prostate cancer (PC) and Ovarian cancer (OC) are two of the most common types of cancer
that affect the reproductive systems of older men and women. These cancers are associated …

Associations between common contraceptive use and circulating inflammatory biomarkers

JM Mongiovi, A Babic, N Sasamoto… - American Journal of …, 2024 - academic.oup.com
Ovarian cancer incidence has declined in recent decades, due in part to oral contraceptive
(OC) use and tubal ligation. However, intrauterine device (IUD) use has increasingly …

Prospective analysis of circulating biomarkers and ovarian cancer risk in the UK Biobank

N Sasamoto, CA Hathaway, MK Townsend… - Cancer Epidemiology …, 2024 - aacrjournals.org
Background: Risk factors have a limited ability to predict individuals at high risk of
developing ovarian cancer among average-risk women, highlighting the need for discovery …

[HTML][HTML] Transcriptome analysis reveals the clinical significance of CXCL13 in Pan-Gyn tumors

Y Ding, Q Zhou, B Ding, Y Zhang, Y Shen - Journal of Cancer Research …, 2024 - Springer
Background Gynecologic and breast tumors (Pan-Gyn) exhibit similar characteristics, and
the role of CXCL13 in anti-tumor immunity and it's potential as a biomarker for immune …