Gene ontology consortium: going forward

Gene Ontology Consortium - Nucleic acids research, 2015 - academic.oup.com
Abstract The Gene Ontology (GO; http://www. geneontology. org) is a community-based
bioinformatics resource that supplies information about gene product function using …

TFClass: expanding the classification of human transcription factors to their mammalian orthologs

E Wingender, T Schoeps, M Haubrock… - Nucleic acids …, 2018 - academic.oup.com
TFClass is a resource that classifies eukaryotic transcription factors (TFs) according to their
DNA-binding domains (DBDs), available online at http://tfclass. bioinf. med. uni-goettingen …

TFClass: an expandable hierarchical classification of human transcription factors

E Wingender, T Schoeps, J Dönitz - Nucleic acids research, 2013 - academic.oup.com
Abstract TFClass (http://tfclass. bioinf. med. uni-goettingen. de/) provides a comprehensive
classification of human transcription factors based on their DNA-binding domains …

iBeetle-Base: a database for RNAi phenotypes in the red flour beetle Tribolium castaneum

J Dönitz, C Schmitt-Engel, D Grossmann… - Nucleic acids …, 2015 - academic.oup.com
Abstract The iBeetle-Base (http://ibeetle-base. uni-goettingen. de) makes available
annotations of RNAi phenotypes, which were gathered in a large scale RNAi screen in the …

TFClass: a classification of human transcription factors and their rodent orthologs

E Wingender, T Schoeps, M Haubrock… - Nucleic acids …, 2015 - academic.oup.com
TFClass aims at classifying eukaryotic transcription factors (TFs) according to their DNA-
binding domains (DBDs). For this, a classification schema comprising four generic levels …

A solution to the challenges of interdisciplinary aggregation and use of specimen-level trait data

MA Balk, J Deck, KF Emery, RL Walls, D Reuter… - Iscience, 2022 - cell.com
Understanding variation of traits within and among species through time and across space is
central to many questions in biology. Many resources assemble species-level trait data, but …

Expanded and updated data and a query pipeline for iBeetle-Base

J Dönitz, L Gerischer, S Hahnke, S Pfeiffer… - Nucleic Acids …, 2018 - academic.oup.com
The iBeetle-Base provides access to sequence and phenotype information for genes of the
beetle Tribolium castaneum. It has been updated including more and updated data and new …

Towards semantic interoperability: finding and repairing hidden contradictions in biomedical ontologies

LT Slater, GV Gkoutos, R Hoehndorf - BMC Medical Informatics and …, 2020 - Springer
Background Ontologies are widely used throughout the biomedical domain. These
ontologies formally represent the classes and relations assumed to exist within a domain. As …

New associations between drug-induced adverse events in animal models and humans reveal novel candidate safety targets

KA Giblin, D Basili, AM Afzal… - Chemical Research …, 2020 - ACS Publications
To improve our ability to extrapolate preclinical toxicity to humans, there is a need to
understand and quantify the concordance of adverse events (AEs) between animal models …

TrOn: An Anatomical Ontology for the Beetle Tribolium castaneum

J Dönitz, D Grossmann, I Schild, C Schmitt-Engel… - PloS one, 2013 - journals.plos.org
In a morphological ontology the expert's knowledge is represented in terms, which describe
morphological structures and how these structures relate to each other. With the assistance …