Human health is determined by the interaction of our environment with the genome,
epigenome, and microbiome, which shape the transcriptomic, proteomic, and metabolomic …

Background Per-and polyfluoroalkyl substances (PFAS) are synthetic chemicals linked to
adverse pregnancy outcomes. Although their underlying biological mechanisms are not fully …

Background Gestational exposure to environmental chemicals (ECs) is associated with
adverse, sex-specific offspring health effects of global concern. As the maternal steroid …

Aim To explore the effect of mixed exposure to per-and polyfluoroalkyl substances (PFAS)
on metabolic syndrome (MetS). Methods This cross-sectional study used data from the …

Environmental toxicants can regulate gene expression in the absence of DNA mutations via
epigenetic mechanisms such as DNA methylation, histone modifications, and non-coding …

Background: Maternal exposure to environmental chemicals can cause adverse health
effects in offspring. Mounting evidence supports that these effects are influenced, at least in …

The placenta is crucial for fetal development, is affected by PFAS toxicity, and evidence is
accumulating that gestational PFAS perturb the epigenetic activity of the placenta …

Epidemiological studies show that exposure to the organochlorine pesticide dieldrin is
associated with increased risk of Parkinson's disease (PD). Animal studies support a link …