Unadulterated BODIPY nanoparticles for biomedical applications

T Zhang, C Ma, T Sun, Z Xie - Coordination Chemistry Reviews, 2019 - Elsevier
Difluoro-4-bora-3a, 4a-diaza-s-indacene (BODIPY) as the robust dyes have been widely
applied in biomedical areas, especially for tumor imaging and phototherapy. Most of the …

Nuclear Imaging of Glucose Metabolism: Beyond 18F‐FDG

H Feng, X Wang, J Chen, J Cui, T Gao… - Contrast media & …, 2019 - Wiley Online Library
Glucose homeostasis plays a key role in numerous fundamental aspects of life, and its
dysregulation is associated with many important diseases such as cancer. The atypical …

Preparation and Bioevaluation of 99mTc-Labeled FAP Inhibitors as Tumor Radiotracers to Target the Fibroblast Activation Protein

Q Ruan, J Feng, Y Jiang, X Zhang, X Duan… - Molecular …, 2021 - ACS Publications
Fibroblast activation protein (FAP) is overexpressed in cancer-associated fibroblasts (CAFs)
in a majority of human epithelial cancers. With low expression in normal organs, FAP has …

Current status and future perspective of radiopharmaceuticals in China

J Hu, H Li, Y Sui, J Du - European Journal of Nuclear Medicine and …, 2022 - Springer
Radiopharmaceuticals are essential components of nuclear medicine and serve as one of
the cornerstones of molecular imaging and precision medicine. They provide new means …

Diphosphine bioconjugates via Pt (0)-catalyzed hydrophosphination. A versatile chelator platform for technetium-99m and rhenium-188 radiolabeling of biomolecules

RE Nuttall, TT Pham, AC Chadwick… - Inorganic …, 2023 - ACS Publications
The ability to append targeting biomolecules to chelators that efficiently coordinate to the
diagnostic imaging radionuclide, 99mTc, and the therapeutic radionuclide, 188Re, can …

Smart bimodal imaging of hypochlorous acid in vivo using a heterobimetallic ruthenium (II)–gadolinium (III) complex probe

W Shi, B Song, Z Liu, W Zhang, M Tan, F Song… - Analytical …, 2020 - ACS Publications
A unique heterobimetallic Ru (II)–Gd (III) complex, Ru-AN-Gd, is reported to serve as an
effective probe for bimodal phosphorescence-magnetic resonance (MR) imaging of …

The Preparation and Execution of Exploratory Human Studies on Novel 99mTc-Labeled Glucosamine Derivatives Containing Different Phenyl Isonitriles as Promising …

Q Wang, Q Gan, Y Jiang, D Xiao, X Chen… - ACS Pharmacology & …, 2023 - ACS Publications
As the “molecule of the century”, 2-deoxy-2-[18F] fluoro-d-glucose ([18F] FDG) is a
radioactive 18F-labeled glucose derivative with a wide range of applications for positron …

Novel 99mTc-Labeled Mannose Derivative as a Highly Promising Single Photon Emission Computed Tomography Probe for Tumor Imaging

G Yin, Q Ruan, Y Jiang, J Feng, P Han… - Journal of Medicinal …, 2024 - ACS Publications
18F-2-fluoro-2-deoxy-d-glucose ([18F] FDG) has been the most used positron emission
tomography imaging agent for clinical applications. Single photon emission computed …

Synthesis and Evaluation of 99mTc-Labelled 2-Nitroimidazole Derivatives with Different Linkers for Tumour Hypoxia Imaging

Q Ruan, Y Liu, L Liao, J Hao, Y Jiang, J Jiang, J Zhang - Pharmaceuticals, 2023 - mdpi.com
When developing novel radiopharmaceuticals, a linker moiety between the chelator and
targeting vector can have a crucial influence on adjusting the affinity of the tracer and its …

A dual-modal nanoprobe based on Eu (III) complex–MnO 2 nanosheet nanocomposites for time-gated luminescence–magnetic resonance imaging of glutathione in …

B Song, W Shi, W Shi, X Qin, H Ma, M Tan, W Zhang… - Nanoscale, 2019 - pubs.rsc.org
Dual-modal fluorescence–magnetic resonance imaging (MRI) techniques have gained great
interest in biomedical research and clinical practice, since they integrate the advantages of …