Bone morphogenetic proteins (BMPs) are multi-functional growth factors belonging to the
Transforming Growth Factor-Beta (TGF-β) superfamily. These proteins are essential to many …

Preeclampsia (PE) is a multifactorial pregnancy disease, characterized by new-onset
gestational hypertension with (or without) proteinuria or end-organ failure, exclusively …

The TGF-β (transforming growth factor-β) system signals via protein kinase receptors and
Smad mediators to regulate a plethora of biological processes, including morphogenesis …

Hereditary haemorrhagic telangiectasia, inherited as an autosomal dominant trait, affects
approximately 1 in 5000 people. The abnormal vascular structures in HHT result from …

Transforming growth factor beta (TGF-β) has been recognized as an important mediator in
the genesis of chronic kidney diseases (CKD), which are characterized by the accumulation …

Endothelial dysfunction is one of the earliest indicators of cardiovascular (CV) dysfunction,
and its evaluation would be of considerable importance to stratify CV risk of many diseases …

Mesenchymal stromal cells (MSCs) are characterized by a regulatory phenotype and
respond promptly to the environmental signals modulating their secretory activity. An …

Over the past decades, there has been an exponential increase in the development of
preclinical and clinical nanodelivery systems, and recently, an accelerating demand to …

Ultrasound (US) imaging is an exquisite tool for the non-invasive and real-time diagnosis of
many different diseases. In this context, US contrast agents can improve lesion delineation …

Despite its limited regenerative capacity, the central nervous system (CNS) shares more
repair mechanisms with peripheral tissues than previously recognized. Scar formation is a …