Investigation on the binding behavior of human α1-acid glycoprotein with Janus Kinase inhibitor baricitinib: Multi-spectroscopic and molecular simulation …
SL Jiang, ZY Hu, WJ Wang, L Hu, L Li, SB Kou… - International Journal of …, 2023 - Elsevier
Abstract Baricitinib is a Janus Kinase (JAK) inhibitor that is primarily used to treat moderately
to severely active rheumatoid arthritis in adults and has recently been reported for the …
to severely active rheumatoid arthritis in adults and has recently been reported for the …
Molecular interactions of ceftazidime with bovine serum albumin: Spectroscopic, molecular docking, and DFT analyses
Ceftazidime is a well-known cephalosporin antibiotic included in the World Health
Organization's list of essential medicines. Herein, we investigated the molecular interactions …
Organization's list of essential medicines. Herein, we investigated the molecular interactions …
Interaction mechanism of a cysteine protease inhibitor, odanacatib, with human serum albumin: In vitro and bioinformatics studies
Odanacatib (ODN) is a selective cathepsin K inhibitor that acts as an anti-resorptive agent to
treat osteoporosis. ODN is also found effective in reducing the effect of severe periodontitis …
treat osteoporosis. ODN is also found effective in reducing the effect of severe periodontitis …
Biological Profile of Two Gentiana lutea L. Metabolites Using Computational Approaches and In Vitro Tests
Natural products have been the main source of bioactive molecules for centuries. We tested
the biological profile of two metabolites extracted from Gentiana lutea L. by means of …
the biological profile of two metabolites extracted from Gentiana lutea L. by means of …
In vitro investigation of the binding characteristics of dacomitinib to human α 1-acid glycoprotein: Multispectral and computational modeling
ZY Hu, HY Sui, QF Zhong, L Hu, JH Shi… - … Acta Part A: Molecular …, 2024 - Elsevier
Dacomitinib is a highly selective second-generation tyrosine kinase inhibitor that can
irreversibly bind to tyrosine kinase and is mainly used in the treatment of lung cancer. The …
irreversibly bind to tyrosine kinase and is mainly used in the treatment of lung cancer. The …