Life is a non‐equilibrium state of matter maintained at the expense of energy. Nature uses
predominantly chemical energy stored in thermodynamically activated, but kinetically stable …

Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …

Connecting dynamics to structural data from diverse experimental sources, molecular
dynamics simulations permit the exploration of biological phenomena in unparalleled detail …

Viruses are nanoscale entities containing a nucleic acid genome encased in a protein shell
called a capsid and in some cases are surrounded by a lipid bilayer membrane. This review …

Abstract Hepatitis B Virus (HBV) is a small virus whose genome has only four open reading
frames. We argue that the simplicity of the virion correlates with a complexity of functions for …

We review approaches aimed at deciphering the physical mechanisms responsible for viral
structure and assembly. We discuss the basic principles of condensed matter physics …

Within the materials science community, proteins with cage-like architectures are being
developed as versatile nanoscale platforms for use in protein nanotechnology. Much effort …

Viral capsids are often regarded as inert structural units, but in actuality they display
fascinating dynamics during different stages of their life cycle. With the advent of single …

Self-assembly is a ubiquitous process in synthetic and biological systems, broadly defined
as the spontaneous organization of multiple subunits (macromolecules, particles, etc.) into …

Viral capsids can adopt various geometries, most iconically characterized by icosahedral or
helical symmetries. Importantly, precise control over the size and shape of virus capsids …