[HTML][HTML] EBV-associated diseases: Current therapeutics and emerging technologies
EBV is a prevalent virus, infecting> 90% of the world's population. This is an oncogenic virus
that causes~ 200,000 cancer-related deaths annually. It is, in addition, a significant …
that causes~ 200,000 cancer-related deaths annually. It is, in addition, a significant …
[HTML][HTML] Role of the DEAD-box RNA helicase DDX5 (p68) in cancer DNA repair, immune suppression, cancer metabolic control, virus infection promotion, and human …
F Li, X Ling, S Chakraborty, C Fountzilas… - Journal of Experimental …, 2023 - Springer
There is increasing evidence indicating the significant role of DDX5 (also called p68), acting
as a master regulator and a potential biomarker and target, in tumorigenesis, proliferation …
as a master regulator and a potential biomarker and target, in tumorigenesis, proliferation …
Extrachromosomal circular MiR-17-92 amplicon promotes HCC
S Zou, S Chen, G Rao, G Zhang, M Ma, B Peng… - Hepatology, 2024 - journals.lww.com
Conclusions: These findings delineate the genome-wide eccDNAs profiling of HCC and
highlight the functional significance of miRNA-containing eccDNAs in tumorigenesis …
highlight the functional significance of miRNA-containing eccDNAs in tumorigenesis …
[HTML][HTML] Disheveled3 enhanced EMT and cancer stem-like cells properties via Wnt/β-catenin/c-Myc/SOX2 pathway in colorectal cancer
Z Li, Z Yang, W Liu, W Zhu, L Yin, Z Han, Y Xian… - Journal of Translational …, 2023 - Springer
Background Epithelial-to-mesenchymal transition (EMT) and cancer stem-like cells (CSLCs)
play crucial role in tumor metastasis and drug-resistance. Disheveled3 (DVL3) is involved in …
play crucial role in tumor metastasis and drug-resistance. Disheveled3 (DVL3) is involved in …
[HTML][HTML] AURKAIP1 actuates tumor progression through stabilizing DDX5 in triple negative breast cancer
W Tian, Y Tang, Y Luo, J Xie, S Zheng, Y Zou… - Cell Death & …, 2023 - nature.com
Aurora-A kinase interacting protein 1 (AURKAIP1) has been proved to take an intermediary
role in cancer by functioning as a negative regulator of Aurora-A kinase. However, it remains …
role in cancer by functioning as a negative regulator of Aurora-A kinase. However, it remains …
RNA helicase DEAD‐box protein 5 alleviates nonalcoholic steatohepatitis progression via tethering TSC complex and suppressing mTORC1 signaling
Y Zhang, S Ye, W Lu, J Zhong, Y Leng, T Yang… - Hepatology, 2023 - journals.lww.com
RNA helicase DEAD‐box protein 5 alleviates nonalcoholic stea... : Hepatology RNA
helicase DEAD‐box protein 5 alleviates nonalcoholic steatohepatitis progression via …
helicase DEAD‐box protein 5 alleviates nonalcoholic steatohepatitis progression via …
[HTML][HTML] Role of noncoding RNAs and untranslated regions in cancer: A review
Y Zhang, M Yang, S Yang, F Hong - Medicine, 2022 - journals.lww.com
Cancer is one of the most prevalent diseases worldwide, and poses a threat to human
health. Noncoding RNAs (ncRNAs) constitute most transcripts, but they cannot be translated …
health. Noncoding RNAs (ncRNAs) constitute most transcripts, but they cannot be translated …
RNA helicase DDX5 enables STAT1 mRNA translation and interferon signalling in hepatitis B virus replicating hepatocytes
Objective RNA helicase DDX5 is downregulated during HBV replication and poor prognosis
HBV-related hepatocellular carcinoma (HCC). The objective of this study is to investigate the …
HBV-related hepatocellular carcinoma (HCC). The objective of this study is to investigate the …
Host-virus chimeric events in SARS-CoV-2-infected cells are infrequent and artifactual
The pathogenic mechanisms underlying severe SARS-CoV-2 (severe acute respiratory
syndrome coronavirus 2) infection remain largely unelucidated. High-throughput …
syndrome coronavirus 2) infection remain largely unelucidated. High-throughput …
[HTML][HTML] DDX56 transcriptionally activates MIST1 to facilitate tumorigenesis of HCC through PTEN-AKT signaling
H Zhou, Y Du, X Wei, C Song, J Song, N Xu… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: Hepatocellular carcinoma (HCC) is a primary malignancy of the liver that is the
leading cause of cancer-related mortality worldwide. However, genetic alterations and …
leading cause of cancer-related mortality worldwide. However, genetic alterations and …