Heart failure in the patient with diabetes: Epidemiology, aetiology, prognosis, therapy and the effect of glucose‐lowering medications

DSH Bell, E Goncalves - Diabetes, Obesity and Metabolism, 2019 - Wiley Online Library
In people with type 2 diabetes the frequency of heart failure (HF) is increased and mortality
from HF is higher than with non‐diabetic HF. The increased frequency of HF is attributable to …

Cellular mechanisms and recommended drug-based therapeutic options in diabetic cardiomyopathy

L Dannenberg, S Weske, M Kelm, B Levkau… - Pharmacology & …, 2021 - Elsevier
Diabetes mellitus (DM) is associated with a specific cardiac phenotype characterized by
structural and functional alterations. This so-called diabetic cardiomyopathy (DM CM) is …

Atherogenic index in type 2 diabetes and its relationship with chronic microvascular complications

Z Li, Q Huang, L Sun, T Bao… - International journal of …, 2018 - Wiley Online Library
Objective. This study was designed to investigate risk factors related to atherogenic index of
plasma (AIP), as well as the relationship between AIP and chronic microvascular …

Chicory inulin ameliorates type 2 diabetes mellitus and suppresses JNK and MAPK pathways in vivo and in vitro

C Ning, X Wang, S Gao, J Mu, Y Wang… - Molecular nutrition & …, 2017 - Wiley Online Library
Scope Chicory inulin is a naturally occurring fructan that is conducive to glucose and lipid
metabolism in patients with diabetes mellitus. This study aims to investigate the mechanism …

[HTML][HTML] Cardioprotective and anti-inflammatory effects of G-protein coupled receptor 30 (GPR30) on postmenopausal type 2 diabetic rats

H Azizian, M Khaksari, M Esmailidehaj… - Biomedicine & …, 2018 - Elsevier
Diabetic cardiomyopathy is the most common chronic disease in postmenopausal women,
but the mechanism (s) is unclear. G-protein coupled receptor 30 (GPR30) is one of the …

[HTML][HTML] Sacubitril/valsartan combination enhanced cardiac glycophagy and prevented the progression of murine diabetic cardiomyopathy

DSA Elshenawy, NM Ramadan, VB Abdo… - Biomedicine & …, 2022 - Elsevier
Background Diabetic cardiomyopathy (DCM) is linked to disturbance in cardiac glucose
handling and increased cardiac glycogen storage. This study tested the potential role of …

Cellular protein quality control in diabetic cardiomyopathy: from bench to bedside

N Kaur, R Raja, A Ruiz-Velasco, W Liu - Frontiers in Cardiovascular …, 2020 - frontiersin.org
Heart failure is a serious comorbidity and the most common cause of mortality in diabetes
patients. Diabetic cardiomyopathy (DCM) features impaired cellular structure and function …

Argatroban attenuates diabetic cardiomyopathy in rats by reducing fibrosis, inflammation, apoptosis, and protease-activated receptor expression

Y Bulani, SS Sharma - Cardiovascular Drugs and Therapy, 2017 - Springer
Purpose Chronic diabetes is associated with cardiovascular dysfunctions. Diabetic
cardiomyopathy (DCM) is one of the serious cardiovascular complications associated with …

Activation of Na+/K+-ATPase attenuates high glucose-induced H9c2 cell apoptosis via suppressing ROS accumulation and MAPKs activities by DRm217

X Yan, M Xun, J Li, L Wu, X Dou… - Acta Biochimica et …, 2016 - academic.oup.com
Hyperglycemia is one of the major factors responsible for the myocardial apoptosis and
dysfunction in diabetes. Many studies have proved that there is a close relationship between …

Therapeutic effects of tamoxifen on metabolic parameters and cytokines modulation in rat model of postmenopausal diabetic cardiovascular dysfunction: Role of …

H Azizian, M Khaksari, G Asadikaram, G Sepehri… - International …, 2018 - Elsevier
In postmenopausal women, the risk of diabetic cardiovascular disease drastically increases
compared with that of premenopausal women. In the present study we surveyed the effects …