Antimicrobial pharmacology and its effect on prescribing is quite complex. Selecting an
antibiotic that will optimally treat an infection while minimizing adverse effects and the …

Kidney disease is an increasingly common comorbidity that alters the pharmacokinetics of
many drugs. Prescribing to patients with kidney disease requires knowledge about the drug …

This article is published as part of a supplement sponsored by Kidney Disease: Improving
Global Outcomes (KDIGO). The opinions or views expressed in this supplement are those of …

A change in pharmacokinetics can alter drug exposure and predispose the patient to either
over-or underdosing, potentially resulting in adverse drug reactions or therapeutic failure …

Abstract Background Drug-related problems (DRPs) are common in aged care facilities and
few studies have been conducted to determine the impact of the pharmacist-conducted …

Background Chronic kidney disease (CKD) afflicts many older adults and increases the risk
for medication-related adverse events. Objective The aim of this study was to assess the …

Introduction Adjusting doses of renally cleared medications and/or avoidance of nephrotoxic
medications are standard clinical practices in chronic kidney disease (CKD), albeit the …

Background Elderly patients with chronic kidney disease (CKD) frequently present
comorbidities that put them at risk of polypharmacy and medication-related problems. This …

Purpose The current state of pharmacogenetic data curation and dissemination is described,
and evidence-based resources for applying pharmacogenetic data in clinical practice are …

Objectives To determine how many ambulatory older adults with chronic kidney disease
receive medications that are contraindicated or dosed excessively given their level of renal …