Revisiting Peri‐Aryloxyquinones: From a Forgotten Photochromic System to a Promising Tool for Emerging Applications

AG Lvov, LS Klimenko, VN Bykov… - Chemistry–A European …, 2024 - Wiley Online Library
Emerging applications of photochromic compounds demand new molecular designs that
can be inspired by some long‐known yet currently forgotten classes of photoswitches. In the …

Visible‐and Near‐Infrared Light‐Driven Molecular Photoswitches for Biological Applications

Y Xu, Y Tang, Q Li - Advanced Functional Materials, 2024 - Wiley Online Library
Molecular photoswitches can undergo isomerization under light exposure, making them
uniquely attractive for high spatiotemporal resolution remote control of biological functions …

Isomerization of bioactive acylhydrazones triggered by light or thiols

Z Zhang, GNT Le, Y Ge, X Tang, X Chen, L Ejim… - Nature Chemistry, 2023 - nature.com
The acylhydrazone unit is well represented in screening databases used to find ligands for
biological targets, and numerous bioactive acylhydrazones have been reported. However …

Rhodanine-Based Chromophores: Fast Access to Capable Photoswitches and Application in Light-Induced Apoptosis

L Köttner, F Wolff, P Mayer, E Zanin… - Journal of the American …, 2024 - ACS Publications
Molecular photoswitches are highly desirable in all chemistry-related areas of research.
They provide effective outside control over geometric and electronic changes at the …

Harnessing Light for G-Quadruplex Modulation: Dual Isomeric Effects of an Ortho-Fluoroazobenzene Derivative

M Dudek, L López-Pacios, N Sabouri… - The journal of …, 2024 - ACS Publications
G-quadruplexes (G4s) are important therapeutic and photopharmacological targets in
cancer research. Small-molecule ligands targeting G4s offer a promising strategy to block …

A Photocaged Microtubule‐Stabilising Epothilone Allows Spatiotemporal Control of Cytoskeletal Dynamics

C Schmitt, P Mauker, NA Vepřek… - Angewandte Chemie …, 2024 - Wiley Online Library
The cytoskeleton is essential for spatial and temporal organisation of a wide range of
cellular and tissue‐level processes, such as proliferation, signalling, cargo transport …

Heterocyclic Hemipiperazines: Multistimuli‐Responsive Switches and Sensors for Zinc or Cadmium Ions

V Schäfer, ZL Pianowski - Chemistry–A European Journal, 2024 - Wiley Online Library
Advance in the design of molecular photoswitches‐adapters that convert light into changes
at molecular level‐opens up exciting possibilities in preparing smart polymers, drugs …

Heterocyclic Hemipiperazines: Water‐Compatible Peptide‐Derived Photoswitches

P Gödtel, J Starrett, ZL Pianowski - Chemistry–A European …, 2023 - Wiley Online Library
Hemipiperazines are a recently discovered class of peptide‐derived molecular
photoswitches with high biocompatibility and therapeutic potential. Here, for the first time we …

Halogen Interaction Effects on Chiral Self‐Assemblies on Cyclodipeptide Scaffolds Across Hierarchy

Z Wang, A Hao, P Xing - Small, 2023 - Wiley Online Library
How halogenation affects protein or peptide folding and self‐assembly hierarchically? This
study tries to answer this question by using the halogen bonding mediated self‐assemblies …

Reversible Photocontrol of Microtubule Stability by Spiropyran‐Conjugated Tau‐Derived Peptides

H Inaba, M Sakaguchi, S Watari, S Ogawa… - …, 2023 - Wiley Online Library
Spatiotemporal modulation of microtubules by light has become an important aspect of the
biological and nanotechnological applications of microtubules. We previously developed a …