Dipeptidyl-peptidase IV (DPP4), originally identified as an aminopeptidase in 1960s, is an
ubiquitously expressed protease presented as either a membrane-bound or soluble form …

Background The infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) has rapidly spread all over the world, becoming pandemic. Several studies have shown …

Objective To evaluate the association of dipeptidylpeptidase 4 (DPP‐4; also known as
CD26) with cellular senescence of human cartilage and progression of knee osteoarthritis …

Abstract Dipeptidyl peptidase-4 inhibitors (DPP-4i) have an important place in the
management of type 2 diabetes. The DPP-4 enzyme is ubiquitously distributed throughout …

Rheumatoid arthritis (RA) is an autoimmune disorder that is characterized by increasing
levels of proinflammatory cytokines. The ubiquitous enzyme dipeptidyl peptidase‐4 (DPP4 …

Incretin hormones, including glucagon-like peptide (GLP)-1, GLP-2 and glucose-dependent
insulinotropic polypeptide (GIP), are gastrointestinal peptides secreted from …

Glucocorticoid-induced hyperglycemia (GIH) is an important complication to be managed by
rheumatologists as it can affect morbidity and mortality of patients. Before administration of …

Rheumatoid arthritis (RA) is an autoimmune disorder with a number of risk factors, including
both genetic and environmental. A number of RA risk associated genomic loci has been …

Introduction Current anti-rheumatic drugs are primarily modulating immune cell activation,
yet their effectiveness remained suboptimal. Therefore, novel therapeutics targeting …

Abstract DPP4 (Dipeptidyl-peptidase 4) a versatile protease, emerges as a prominent player
in soluble and membrane-bound forms. Its heightened expression has been intimately …