L-selectin (CD62L) is a type-I transmembrane glycoprotein and cell adhesion molecule that
is expressed on most circulating leukocytes. Since its identification in 1983, L-selectin has …

CD34 is a transmembrane phosphoglycoprotein, first identified on hematopoietic stem and
progenitor cells. Clinically, it is associated with the selection and enrichment of …

Stromal cells (SCs) establish the compartmentalization of lymphoid tissues critical to the
immune response. However, the full diversity of lymph node (LN) SCs remains undefined …

High endothelial venules (HEVs) are specialized blood vessels mediating lymphocyte
trafficking to lymph nodes (LNs) and other secondary lymphoid organs. By supporting high …

Allogeneic natural killer (NK) cell adoptive transfer has shown the potential to induce
remissions in relapsed or refractory leukemias and lymphomas, but strategies to enhance …

Multiple protein families, each with a distinct function, provide the traffic signals for
leukocytes. The selectin family of adhesion molecules (Figure 2) has an N-terminal domain …

Vestweber, Dietmar, and James E. Blanks. Mechanisms That Regulate the Function of the
Selectins and Their Ligands. Physiol. Rev. 79: 181–213, 1999.—Selectins are a family of …

The circulatory and migratory properties of white blood cells have evolved to allow efficient
surveillance of tissues for infectious pathogens and rapid accu ญ mulation at sites of injury …

L-selectin, a cell adhesion molecule expressed by leukocytes, mediates the attachment of
lymphocytes to high endothelial venules (HEV) of peripheral lymph nodes and mediates the …

Neutrophil‐endothelial cell interactions are mediated by interacting sets of cell adhesion
molecules (CAMs) and chemoattractant/activator molecules to form an “adhesion cascade.” …