Promises of phytochemical based nano drug delivery systems in the management of cancer

P Kumar, N Yadav, B Chaudhary, V Jain… - Chemico-Biological …, 2022 - Elsevier
Cancer is the leading cause of human disease and death worldwide, accounting for 7.6
million deaths per year and projected to reach 13.1 million by 2030. Many phytochemicals …

Optimization of the extraction conditions of Nypa fruticans Wurmb. using response surface methodology and artificial neural network

HJ Choi, M Naznin, MB Alam, A Javed, FH Alshammari… - Food Chemistry, 2022 - Elsevier
In this study, we conducted response surface methodology (RSM) and artificial neural
network (ANN) to predict and estimate the optimized extraction condition of Nypa fruticans …

Cytotoxic and chemomodulatory effects of Phyllanthus niruri in MCF-7 and MCF-7ADR breast cancer cells

OE Abdel-Sattar, RM Allam, AM Al-Abd, B Avula… - Scientific Reports, 2023 - nature.com
The members of the genus Phyllanthus have long been used in the treatment of a broad
spectrum of diseases. They exhibited antiproliferative activity against various human cancer …

CORM‐3 Attenuates Oxidative Stress‐Induced Bone Loss via the Nrf2/HO‐1 Pathway

C Jin, B Lin, G Zheng, K Tan, G Liu… - Oxidative Medicine …, 2022 - Wiley Online Library
Bone metabolism occurs in the entire life of an individual and is required for maintaining
skeletal homeostasis. The imbalance between osteogenesis and osteoclastogenesis …

Metabolite profiling of Nymphaea rubra (Burm. f.) flower extracts using cyclic ion mobility–mass spectrometry and their associated biological activities

M Naznin, MB Alam, R Alam, S Islam, S Rakhmat… - Food Chemistry, 2023 - Elsevier
Nymphaea rubra flowers (NRF) are widely used as a food and in folk medicine throughout
the subtropical regions due to their health-promoting characteristics. This study …

[HTML][HTML] Review on edible water lilies and lotus: Future food, nutrition and their health benefits

AL Abelti, TA Teka, G Bultosa - Applied Food Research, 2023 - Elsevier
Water lilies and lotus are regarded as good source of food, nutrition, and medicinal
purposes. This review assessed scientific evidence for application of fifteen species of water …

Profiling of Secondary Metabolites of Optimized Ripe Ajwa Date Pulp (Phoenix dactylifera L.) Using Response Surface Methodology and Artificial Neural Network

F Alshammari, MB Alam, M Naznin, A Javed, S Kim… - Pharmaceuticals, 2023 - mdpi.com
The date palm (Phoenix dactylifera L.) is a popular edible fruit consumed all over the world
and thought to cure several chronic diseases and afflictions. The profiling of the secondary …

Water lily (Nymphaea nouchali Burm. f): an ancient treasure of food and medicine

B Kiranmai, M Sandhyarani, AK Tiwari - Pharmacognosy Research, 2023 - phcogres.com
Nymphaea nouchali (Syn. Nymphaea stellata Willd.) from family Nymphaeaceae, is a
species of perennial aquatic flowering plant with huge round floating leaves and rhizomes. It …

Optimization, Metabolomic Analysis, Antioxidant Potential and Depigmenting Activity of Polyphenolic Compounds from Unmature Ajwa Date Seeds (Phoenix …

F Alshammari, MB Alam, M Naznin, S Kim, SH Lee - Antioxidants, 2024 - mdpi.com
This study sought to optimize the ultrasonic-assisted extraction of polyphenolic compounds
from unmature Ajwa date seeds (UMS), conduct untargeted metabolite identification and …

The activation of Nrf2/HO-1 by 8-Epi-7-deoxyloganic acid attenuates inflammatory symptoms through the suppression of the MAPK/NF-κB signaling cascade in in vitro …

SY Simu, MB Alam, SY Kim - Antioxidants, 2022 - mdpi.com
In this study, we examined the ameliorative effects of 8-epi-7-deoxyloganic acid (DLA), an
iridoid glycoside, on oxidative stress and inflammation in both LPS-stimulated macrophages …