Membrane-based techniques for the separation and purification of proteins: An overview

A Saxena, BP Tripathi, M Kumar, VK Shahi - Advances in colloid and …, 2009 - Elsevier
Membrane processes are increasingly reported for various applications in both upstream
and downstream technology, such as microfiltration, ultrafiltration, emerging processes as …

Radiation-grafted copolymers for separation and purification purposes: Status, challenges and future directions

MM Nasef, O Güven - Progress in Polymer Science, 2012 - Elsevier
Functional copolymers obtained by modification of existing polymers using radiation
induced graft copolymerization are attractive materials due to their enhanced separation …

[图书][B] Handbook of membrane separations: chemical, pharmaceutical, food, and biotechnological applications

AK Pabby, SSH Rizvi, AMS Requena - 2008 - taylorfrancis.com
The Handbook of Membrane Separations: Chemical, Pharmaceutical, and Biotechnological
Applications provides detailed information on membrane separation technologies as they …

Recent advances in bioprocessing application of membrane chromatography

V Orr, L Zhong, M Moo-Young, CP Chou - Biotechnology advances, 2013 - Elsevier
Compared to traditional chromatography using resins in packed-bed columns, membrane
chromatography is a relatively new and immature bioseparation technology based on the …

Technology trends in antibody purification

P Gagnon - Journal of chromatography A, 2012 - Elsevier
This article reviews technology trends in antibody purification. Section 1 discusses non-
chromatography methods, including precipitation, liquid–liquid extraction, and high …

Protein A chromatography: Challenges and progress in the purification of monoclonal antibodies

AM Ramos‐de‐la‐Peña… - Journal of separation …, 2019 - Wiley Online Library
Antibodies for therapeutic use are being continuously approved and their demand has been
steadily growing. As known, the golden standard for monoclonal antibody (mAb) purification …

Affinity chromatography as a tool for antibody purification

BV Ayyar, S Arora, C Murphy, R O'Kennedy - Methods, 2012 - Elsevier
The global antibody market has grown exponentially due to increasing applications in
research, diagnostics and therapy. Antibodies are present in complex matrices (eg serum …

[HTML][HTML] Overview of albumin and its purification methods

R Raoufinia, A Mota, N Keyhanvar, F Safari… - Advanced …, 2016 - ncbi.nlm.nih.gov
As the most frequent plasma protein, albumin constitutes more than 50% of the serum
proteins in healthy individuals. It has a key role in oncotic pressure maintenance and it is …

Developments and opportunities in continuous biopharmaceutical manufacturing

O Khanal, AM Lenhoff - MAbs, 2021 - Taylor & Francis
Today's biologics manufacturing practices incur high costs to the drug makers, which can
contribute to high prices for patients. Timely investment in the development and …

Chromatography-free recovery of biopharmaceuticals through aqueous two-phase processing

AM Azevedo, PAJ Rosa, IF Ferreira… - Trends in …, 2009 - cell.com
The therapeutic use of proteins has created an increasing demand for feasible and
economical methods for both up-and downstream processes. However, whereas upstream …