Immunomodulatory effect of protocatechuic acid on cyclophosphamide induced brain injury in rat: modulation of inflammosomes NLRP3 and SIRT1

A Salama, R Elgohary, MM Amin… - European Journal of …, 2022 - Elsevier
Modulation of the inflammasome NLRP3 and SIRT1 are new combat strategy for brain injury
protection. The inflammasome activates proinflammatory cytokines releasing interleukin-1β …

[HTML][HTML] How can the commercial potential of microalgae from the Dunaliella genus be improved? The importance of nucleotide metabolism with a focus on …

AM Woyda-Ploszczyca, AS Rybak - Algal Research, 2021 - Elsevier
Over recent decades, wide-ranging research has been focused on algae due to their
potential applications, eg, for biomass, extract and “third”-generation biofuel production. In …

Antioxidant bioprospecting in microalgae: characterisation of the potential of two marine heterokonts from Irish waters

L Archer, D McGee, R Parkes, A Paskuliakova… - Applied Biochemistry …, 2021 - Springer
Microalgae constitute a heterogeneous and diverse range of organisms capable of
accumulating bioactive metabolites, making them promising feedstock for applications in the …

Haematococcus pluvialis Carotenoids Enrich Fractions Ameliorate Liver Fibrosis Induced by Thioacetamide in Rats: Modulation of Metalloproteinase and Its Inhibitor

FK El-Baz, A Salama, SI Ali… - BioMed research …, 2021 - Wiley Online Library
Hepatic fibrosis is a consequence of chronic liver diseases. Metalloproteinase and its
inhibitor have crucial roles in the resolution of liver fibrosis. The current relevant study is …

Innovated pirfenidone loaded lecithin nanocapsules for targeting liver fibrosis: Formulation, characterization and in vivo study

MM AbouSamra, R Elgohary, SS Mansy - International Journal of …, 2023 - Elsevier
Increasing interest in developing antifibrotic therapies became a paramount priority due to
the globally raised incidence of deaths secondary to hepatic cirrhosis. This work deals with …

[HTML][HTML] Dunaliella salina chitosan nanoparticles as a promising wound healing vehicles: In-vitro and in-vivo study

FK El-Baz, A Salama, SI Ali, HA El-Hashemy - OpenNano, 2023 - Elsevier
Dunaliella salina, a green microalga, is among the main sources of bioactive β-carotene and
zeaxanthin. Hence, it will be investigated for its antioxidant effectiveness in wound healing …

Chrysin–phospholipid complex-based solid dispersion for improved anti-aging and neuroprotective effects in mice

A Salama, R Elgohary, AA Kassem… - Pharmaceutical …, 2023 - Taylor & Francis
The present study aimed to improve the neuroprotective effect of chrysin (CHR) by
combining two formulation techniques, phospholipid (PL) complexation and solid dispersion …

Optimizing the extraction of carotenoids and omega fatty acids from microalgae

FK El-Baz, SI Ali - Egyptian Journal of Chemistry, 2023 - ejchem.journals.ekb.eg
Microalgae are the most significant renewable sources of natural carotenoids and omega
fatty acids. These include Dunaliella salina, Haematococcus pluvialis, and Scenedesmus …

Effect of the Emulsifier Used in Dunaliella salina‐Based Nanoemulsions Formulation on the β‐Carotene Absorption and Metabolism in Rats

J Teixé‐Roig, G Oms‐Oliu… - Molecular Nutrition & …, 2023 - Wiley Online Library
Scope Microalgae such as Dunaliella salina are a potential sustainable source of natural β‐
carotene due to their fast growth and high adaptability to environmental conditions. This …

Astaxanthin- Enriched Fraction from the Microalga Haematococcus pluvialis Mitigates Kidney Injury via Modulation of Nrf2/Keap1 and MAPK/ERK Pathways in Rats

FK El-Baz, SI Ali, A Salama, R Elgohary - Revista Brasileira de …, 2023 - Springer
Acute kidney injury is a complication of using gentamicin in high doses and is associated
with severe morbidity and mortality. Astaxanthin, the red xanthophyll carotenoid pigment …