The synaptic plasticity and memory hypothesis asserts that activity-dependent synaptic
plasticity is induced at appropriate synapses during memory formation and is both …

Consolidation of implicit memory in the invertebrate Aplysia and explicit memory in the
mammalian hippocampus are associated with remodeling and growth of preexisting …

The discovery of long‐term potentiation (LTP) provided the first, direct evidence for long‐
lasting synaptic plasticity in the living brain. Consequently, LTP was proposed to serve as a …

In 1973, two papers from Bliss and Lømo and from Bliss and Gardner-Medwin reported that
high-frequency synaptic stimulation in the dentate gyrus of rabbits resulted in a long-lasting …

Repetitive behaviors are a key feature of many pervasive developmental disorders, such as
autism. As a heterogeneous group of symptoms, repetitive behaviors are conceptualized …

Hippocampal long-term potentiation (LTP) is a model system for studying cellular
mechanisms of learning and memory. Recent interest in mechanisms underlying the …

While a maternal diet high in saturated fat is likely to affect foetal brain development,
whether the effects are the same for male and female offspring is unclear. As a result, we …

Accumulation of amyloid plaques comprises one of the major hallmarks of Alzheimer's
disease (AD). In rodents, acute treatment with amyloid-beta (Aβ; 1–42) elicits immediate …

Under physiological conditions, strength and persistence of memory must be regulated in
order to produce behavioral flexibility. In fact, impairments in memory flexibility are …

Recent evidence indicates that soluble amyloid‐β (Aβ) species induce imbalances in
excitatory and inhibitory transmission, resulting in neural network functional impairment and …