Testicular cancer
Testicular cancer is the most common malignancy among men between 14 and 44 years of
age, and its incidence has risen over the past two decades in Western countries. Both …
age, and its incidence has risen over the past two decades in Western countries. Both …
Male reproductive disorders and fertility trends: influences of environment and genetic susceptibility
NE Skakkebaek, E Rajpert-De Meyts… - Physiological …, 2016 - journals.physiology.org
It is predicted that Japan and European Union will soon experience appreciable decreases
in their populations due to persistently low total fertility rates (TFR) below replacement level …
in their populations due to persistently low total fertility rates (TFR) below replacement level …
Testicular germ cell tumours
E Rajpert-De Meyts, KA McGlynn, K Okamoto… - The Lancet, 2016 - thelancet.com
Testicular germ cell tumours are at the crossroads of developmental and neoplastic
processes. Their cause has not been fully elucidated but differences in incidences suggest …
processes. Their cause has not been fully elucidated but differences in incidences suggest …
What is trophoblast? A combination of criteria define human first-trimester trophoblast
Controversy surrounds reports describing the derivation of human trophoblast cells from
placentas and embryonic stem cells (ESC), partly due to the difficulty in identifying markers …
placentas and embryonic stem cells (ESC), partly due to the difficulty in identifying markers …
[HTML][HTML] Circulating MicroRNAs, the next-generation serum biomarkers in testicular germ cell tumours: a systematic review
Context Clinical management of testicular germ cell tumours (GCTs) is hampered by low
sensitivity and specificity of the biomarkers currently in use. Circulating microRNAs (miRs) …
sensitivity and specificity of the biomarkers currently in use. Circulating microRNAs (miRs) …
Human germ cell tumors are developmental cancers: impact of epigenetics on pathobiology and clinic
J Lobo, AJM Gillis, C Jerónimo, R Henrique… - International journal of …, 2019 - mdpi.com
Current (high throughput omics-based) data support the model that human (malignant) germ
cell tumors are not initiated by somatic mutations, but, instead through a defined locked …
cell tumors are not initiated by somatic mutations, but, instead through a defined locked …
The present and future of serum diagnostic tests for testicular germ cell tumours
MJ Murray, RA Huddart, N Coleman - Nature Reviews Urology, 2016 - nature.com
Testicular germ cell tumours (GCTs) are the most common malignancy occurring in young
adult men and the incidence of these tumours is increasing. Current research priorities in …
adult men and the incidence of these tumours is increasing. Current research priorities in …
Application of miRNAs in the diagnosis and monitoring of testicular germ cell tumours
Testicular germ cell tumours (TGCTs) are the most frequent cancer type in young men and
originate from the common precursor germ cell neoplasia in situ (GCNIS). For decades …
originate from the common precursor germ cell neoplasia in situ (GCNIS). For decades …
[HTML][HTML] MicroRNA expression profiles in human testicular tissues of infertile men with different histopathologic patterns
Objective To investigate the expression profiles of microRNA (miRNA) in human testes
showing different histopathological patterns. Design Microarray with quantitative real-time …
showing different histopathological patterns. Design Microarray with quantitative real-time …
[HTML][HTML] Targeted serum miRNA (TSmiR) test for diagnosis and follow-up of (testicular) germ cell cancer patients: a proof of principle
AJM Gillis, MA Rijlaarsdam, R Eini, LCJ Dorssers… - Molecular …, 2013 - Elsevier
Germ cell cancers (GCC) are the most frequent malignancy in young Caucasian males.
GCC can consist of seminomas (SE) and non-seminomas (malignant NS: embryonal …
GCC can consist of seminomas (SE) and non-seminomas (malignant NS: embryonal …