The interaction of bacterial pathogens with mammalian hosts leads to a variety of
physiological responses of the interacting partners aimed at an adaptation to the new …

The HtrA family of chaperones and serine proteases is important for regulating stress
responses and controlling protein quality in the periplasm of bacteria. HtrA is also …

The periplasmic chaperone and serine protease HtrA is important for bacterial stress
responses and protein quality control. Recently, we discovered that HtrA from Helicobacter …

Bacterial pathogens rely on proteolysis for variety of purposes during the infection process.
In the cytosol, the main proteolytic players are the conserved Clp and Lon proteases that …

The HtrA proteases degrade damaged proteins and thus control the quality of proteins and
protect cells against the consequences of various stresses; they also recognize specific …

Chlamydia trachomatis serovars are obligate intracellular bacterial pathogens mainly
causing ocular and urogenital infections that affect millions of people worldwide and which …

Background Outer membrane vesicles (OMVs) are spheroid particles released by all Gram-
negative bacteria as a result of the budding out of the outer membrane. Since they carry …

Research in Chlamydia trachomatis and Chlamydia pneumoniae has gained new traction
due to recent advances in molecular biology, namely the widespread use of the …

Metabolic adaptation reactions are common when prokaryotes interact with eukaryotic cells,
especially when the bacteria are internalized by these host cells. Such adaptations lead to …

The ability to exit host cells at the end of their developmental growth is a critical step for the
intracellular bacterium Chlamydia. One exit strategy, extrusion, is mediated by host signaling …