Position statement of the World Heart Federation on the prevention and control of rheumatic heart disease
In the 21st century, rheumatic fever (RF) and rheumatic heart disease (RHD) are neglected
diseases of marginalized communities. Globally, RHD remains the most-common …
diseases of marginalized communities. Globally, RHD remains the most-common …
Molecular epidemiology, ecology, and evolution of group A streptococci
DE Bessen, PR Smeesters, BW Beall - Microbiology spectrum, 2018 - Am Soc Microbiol
The clinico-epidemiological features of diseases caused by group A streptococci (GAS) is
presented through the lens of the ecology, population genetics, and evolution of the …
presented through the lens of the ecology, population genetics, and evolution of the …
The classical lancefield antigen of group a Streptococcus is a virulence determinant with implications for vaccine design
Summary Group A Streptococcus (GAS) is a leading cause of infection-related mortality in
humans. All GAS serotypes express the Lancefield group A carbohydrate (GAC), comprising …
humans. All GAS serotypes express the Lancefield group A carbohydrate (GAC), comprising …
Differing efficacies of lead group A streptococcal vaccine candidates and full-length M protein in cutaneous and invasive disease models
ABSTRACT Group A Streptococcus (GAS) is an important human pathogen responsible for
both superficial infections and invasive diseases. Autoimmune sequelae may occur upon …
both superficial infections and invasive diseases. Autoimmune sequelae may occur upon …
A synthetic M protein peptide synergizes with a CXC chemokine protease to induce vaccine-mediated protection against virulent streptococcal pyoderma and …
Infections caused by Streptococcus pyogenes (group A Streptococcus [GAS]) are highly
prevalent in the tropics, in developing countries, and in the Indigenous populations of …
prevalent in the tropics, in developing countries, and in the Indigenous populations of …
Self-assembly of trimethyl chitosan and poly (anionic amino acid)-peptide antigen conjugate to produce a potent self-adjuvanting nanovaccine delivery system
Short peptides derived from virulent pathogen proteins are promising antigens for the
development of vaccines against infectious diseases. However, in order to mimic the danger …
development of vaccines against infectious diseases. However, in order to mimic the danger …
Combinatorial synthetic peptide vaccine strategy protects against hypervirulent CovR/S mutant streptococci
M Pandey, R Mortensen, A Calcutt, J Powell… - The Journal of …, 2016 - journals.aai.org
Cluster of virulence responder/sensor (CovR/S) mutant group A streptococci (GAS) are
serious human pathogens of multiple M protein strains that upregulate expression of …
serious human pathogens of multiple M protein strains that upregulate expression of …
Group A Streptococcal vaccine candidate: contribution of epitope to size, antigen presenting cell interaction and immunogenicity
Aim: Utilize lipopeptide vaccine delivery system to develop a vaccine candidate against
Group A Streptococcus. Materials & methods: Lipopeptides synthesized by solid-phase …
Group A Streptococcus. Materials & methods: Lipopeptides synthesized by solid-phase …
Health system and patient-level factors serving as facilitators and barriers to rheumatic heart disease care in Sudan
JG Edwards, M Barry, D Essam, M Elsayed… - Global Health Research …, 2021 - Springer
Background Rheumatic heart disease (RHD) remains a leading cause of morbidity and
mortality in Sub-Saharan Africa despite widely available preventive therapies such as …
mortality in Sub-Saharan Africa despite widely available preventive therapies such as …
Epidemiology of infective endocarditis: novel aspects in the twenty-first century
V Arshad, KM Talha, LM Baddour - Expert Review of …, 2022 - Taylor & Francis
Introduction The epidemiology of infective endocarditis (IE) in this millennium has changed
with emergence of new risk factors and reemergence of others. This, coupled with …
with emergence of new risk factors and reemergence of others. This, coupled with …