[PDF][PDF] Novel approaches for vaccine development
MS Gebre, LA Brito, LH Tostanoski, DK Edwards… - Cell, 2021 - cell.com
Vaccines are critical tools for maintaining global health. Traditional vaccine technologies
have been used across a wide range of bacterial and viral pathogens, yet there are a …
have been used across a wide range of bacterial and viral pathogens, yet there are a …
[HTML][HTML] The emergence of Zika virus and its new clinical syndromes
TC Pierson, MS Diamond - Nature, 2018 - nature.com
Zika virus (ZIKV) is a mosquito-transmitted flavivirus that has emerged as a global health
threat because of its potential to generate explosive epidemics and ability to cause …
threat because of its potential to generate explosive epidemics and ability to cause …
[HTML][HTML] Immunization against Zika by entrapping live virus in a subcutaneous self-adjuvanting hydrogel
H Hao, S Wu, J Lin, Z Zheng, Y Zhou, Y Zhang… - Nature Biomedical …, 2023 - nature.com
The threat of new viral outbreaks has heightened the need for ready-to-use vaccines that are
safe and effective. Here we show that a subcutaneous vaccine consisting of live Zika virus …
safe and effective. Here we show that a subcutaneous vaccine consisting of live Zika virus …
Zika, chikungunya, and other emerging vector-borne viral diseases
Arthropod-borne viruses (arboviruses) have a long history of emerging to infect humans, but
during recent decades, they have been spreading more widely and affecting larger …
during recent decades, they have been spreading more widely and affecting larger …
[HTML][HTML] An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction
Virus–host interactions determine an infection outcome. The Asian lineage of Zika virus
(ZIKV), responsible for the recent epidemics, has fixed a mutation in the NS1 gene after …
(ZIKV), responsible for the recent epidemics, has fixed a mutation in the NS1 gene after …
[HTML][HTML] Current status of Zika virus vaccines: successes and challenges
The recently emerged Zika virus (ZIKV) spread to the Americas, causing a spectrum of
congenital diseases including microcephaly in newborn and Guillain-Barré syndrome (GBS) …
congenital diseases including microcephaly in newborn and Guillain-Barré syndrome (GBS) …
[PDF][PDF] Vaccine mediated protection against Zika virus-induced congenital disease
The emergence of Zika virus (ZIKV) and its association with congenital malformations has
prompted the rapid development of vaccines. Although efficacy with multiple viral vaccine …
prompted the rapid development of vaccines. Although efficacy with multiple viral vaccine …
[HTML][HTML] Viral emerging diseases: challenges in developing vaccination strategies
In the last decades, a number of infectious viruses have emerged from wildlife or re-
emerged, generating serious threats to the global health and to the economy worldwide …
emerged, generating serious threats to the global health and to the economy worldwide …
Structural biology of Zika virus and other flaviviruses
Zika virus (ZIKV) is an enveloped, icosahedral flavivirus that has structural and functional
similarities to other human flavivirus pathogens such as dengue (DENV), West Nile (WNV) …
similarities to other human flavivirus pathogens such as dengue (DENV), West Nile (WNV) …
[HTML][HTML] Current advances in Zika vaccine development
Y Wang, L Ling, Z Zhang, A Marin-Lopez - Vaccines, 2022 - mdpi.com
Zika virus (ZIKV), an emerging arthropod-borne flavivirus, was first isolated in Uganda in
1947 from monkeys and first detected in humans in Nigeria in 1952; it has been associated …
1947 from monkeys and first detected in humans in Nigeria in 1952; it has been associated …