Inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis, is a
chronic, relapsing immune-mediated disease with a varying and sometimes severe disease …

Chronic visceral pain syndromes are important clinical problems with largely unmet medical
needs. Based on the common overlap with other chronic disorders of visceral or somatic …

Alterations in gray matter (GM) density/volume and cortical thickness (CT) have been
demonstrated in small and heterogeneous samples of subjects with differing chronic pain …

BackgroundCentral nervous system (CNS) dysfunction is a prominent feature of the
functional gastrointestinal (GI) disorder, irritable bowel syndrome (IBS). However, the …

Background Fatigue is the inability to achieve or maintain an expected work output resulting
from central or peripheral mechanisms. The prevalence of inflammatory bowel disease (IBD) …

Ulcerative colitis and Crohn's disease, commonly known as inflammatory bowel disease
(IBD), draw attention from specialists of various disorders, including gastroenterology …

Significance: The p53 family of transcription factors, including p53, p63, and p73, plays key
roles in both biological and pathological processes, including cancer and neural …

Most gastrointestinal diseases and disorders (GIDD) are associated with depression,
anxiety, and cognitive dysfunction. This suggests that shared features of GIDD, particularly …

Background A growing number of neuroimaging studies suggest distinct neural changes in
inflammatory bowel diseases (IBDs). Whether such changes may show similar spatial …

Abstract Background: Whether Crohn's disease [CD] is correlated with brain structural
changes is unclear. This study examined changes in grey matter [GM] structures in CD …