Superoxide, O2•−, is formed in all living organisms that come in contact with air, and,
depending upon its biological context, it may act as a signaling agent, a toxic species, or a …

Transition metals occupy an essential niche in biological systems. Their electrostatic
properties stabilize substrates or reaction intermediates in the active sites of enzymes, and …

Deinococcus radiodurans is a robust bacterium best known for its capacity to repair massive
DNA damage efficiently and accurately. It is extremely resistant to many DNA-damaging …

Bacterial lipoproteins are a set of membrane proteins with many different functions. Due to
this broad-ranging functionality, these proteins have a considerable significance in many …

Mononuclear iron enzymes can tightly bind non-activating metals. How do cells avoid
mismetallation? The model bacterium Escherichia coli may control its metal pools so that …

The redox-active metal manganese plays a key role in cellular adaptation to oxidative stress.
As a cofactor for manganese superoxide dismutase or through formation of non …

For decades after its introduction, the mechanisms of action of the front‐line antituberculosis
therapeutic agent isoniazid (INH) remained unclear. Recent developments have shown that …

The field of free radical biology originated with the discovery of superoxide dismutase (SOD)
in 1969. Over the last 5 decades, a plethora of research has been performed in species …

The molecular mechanisms used by the gonococcus to initiate infection exhibit gender
specificity. The clinical presentations of disease are also strikingly different upon comparison …

Very little manganese is imported into Escherichia coli under routine growth conditions: the
import system is weakly expressed, the manganese content is low, and a manganese …