Ultrasensitive and highly specific lateral flow assays for point-of-care diagnosis

Y Liu, L Zhan, Z Qin, J Sackrison, JC Bischof - ACS nano, 2021 - ACS Publications
Lateral flow assays (LFAs) are paper-based point-of-care (POC) diagnostic tools that are
widely used because of their low cost, ease of use, and rapid format. Unfortunately …

Diagnosing COVID-19: the disease and tools for detection

B Udugama, P Kadhiresan, HN Kozlowski… - ACS …, 2020 - ACS Publications
COVID-19 has spread globally since its discovery in Hubei province, China in December
2019. A combination of computed tomography imaging, whole genome sequencing, and …

[HTML][HTML] Massively multiplexed nucleic acid detection with Cas13

CM Ackerman, C Myhrvold, SG Thakku, CA Freije… - Nature, 2020 - nature.com
The great majority of globally circulating pathogens go undetected, undermining patient care
and hindering outbreak preparedness and response. To enable routine surveillance and …

Field-deployable viral diagnostics using CRISPR-Cas13

C Myhrvold, CA Freije, JS Gootenberg, OO Abudayyeh… - Science, 2018 - science.org
Mitigating global infectious disease requires diagnostic tools that are sensitive, specific, and
rapidly field deployable. In this study, we demonstrate that the Cas13-based SHERLOCK …

The era of digital health: A review of portable and wearable affinity biosensors

J Tu, RM Torrente‐Rodríguez… - Advanced Functional …, 2020 - Wiley Online Library
Digital health facilitated by wearable/portable electronics and big data analytics holds great
potential in empowering patients with real‐time diagnostics tools and information. The …

[HTML][HTML] Dengue virus infection–a review of pathogenesis, vaccines, diagnosis and therapy

BH Kok, HT Lim, CP Lim, NS Lai, CY Leow, CH Leow - Virus research, 2023 - Elsevier
The transmission of dengue virus (DENV) from an infected Aedes mosquito to a human,
causes illness ranging from mild dengue fever to fatal dengue shock syndrome. The similar …

Recent advances in nanoparticle-based lateral flow immunoassay as a point-of-care diagnostic tool for infectious agents and diseases

R Banerjee, A Jaiswal - Analyst, 2018 - pubs.rsc.org
Lateral flow immunoassay (LFIA) technology is a paper-based, point-of-care strip biosensor
designed to detect a specific analyte in a given sample. This type of assay is now of great …

Strategies for developing sensitive and specific nanoparticle-based lateral flow assays as point-of-care diagnostic device

JH Soh, HM Chan, JY Ying - Nano Today, 2020 - Elsevier
From a home-based pregnancy self-testing kit, lateral flow assays (LFAs) have proliferated
and gained widespread utilization as point-of-care (POC) test kits. Their prevalence is due to …

Trends and innovations in biosensors for COVID‐19 mass testing

I Santiago - ChemBioChem, 2020 - Wiley Online Library
Fast and widespread diagnosis is crucial to fighting against the outbreak of COVID‐19. This
work surveys the landscape of available and emerging biosensor technologies for COVID …

From point-of-care testing to eHealth diagnostic devices (eDiagnostics)

DC Christodouleas, B Kaur, P Chorti - ACS Central Science, 2018 - ACS Publications
Point-of-care devices were originally designed to allow medical testing at or near the point of
care by health-care professionals. Some point-of-care devices allow medical self-testing at …