Early versus deferred antiretroviral multidrug therapy in infants infected with HIV type 1

A Faye, J Le Chenadec, C Dollfus… - Clinical infectious …, 2004 - academic.oup.com
Background. The clinical impact of early antiretroviral multidrug therapy on the risk of early-
onset severe human immunodeficiency virus (HIV) disease has not been evaluated on a …

The vertical transmission of human immunodeficiency virus type 1: molecular and biological properties of the virus

N Ahmad - Critical Reviews in Clinical Laboratory Sciences, 2005 - Taylor & Francis
The vertical (mother-to-infant) transmission of human immunodeficiency virus type 1 (HIV-1)
occurs at an estimated rate of more than 30% and is the major cause of AIDS in children …

Long-term effects of highly active antiretroviral therapy in pretreated, vertically HIV type 1-infected children: 6 years of follow-up

S Resino, R Resino, D Micheloud… - Clinical Infectious …, 2006 - academic.oup.com
Background. Several studies of children with human immunodeficiency virus (HIV) type 1
infection have demonstrated sustained increases in CD4+ cell count, even when virological …

[HTML][HTML] Transmission of HIV-1 infection between trophoblast placental cells and T-cells take place via an LFA-1-mediated cell to cell contact

RA Arias, D Laura, MA Muñoz-Fernández - Virology, 2003 - Elsevier
HIV-1 vertical transmission is thought to mainly take place by virus crossing the placental
barrier. However, the mechanism by which HIV-1-infects placental cells remains to be …

A new tool for the paediatric HIV research: general data from the Cohort of the Spanish Paediatric HIV Network (CoRISpe)

MI de Jose, S Jiménez de Ory, M Espiau… - BMC infectious …, 2013 - Springer
There are approximately from 1,100 to 1,200 HIV-infected children in a follow-up in Spain. In
2008 an open, multicentral, retrospective and prospective Cohort of the Spanish Paediatric …

Low Blood CD8+ T-Lymphocytes and High Circulating Monocytes Are Predictors of HIV-1-Associated Progressive Encephalopathy in Children

S Sánchez-Ramón, J Mͣ Bellón, S Resino… - …, 2003 - publications.aap.org
Objective. Human immunodeficiency virus type 1 (HIV-1)-associated progressive
encephalopathy (PE) is a common and devastating complication of HIV-1 infection in …

CD38 Expression in CD8+ T Cells Predicts Virological Failure in HIV Type 1–Infected Children Receiving Antiretroviral Therapy

S Resino, JM Bellón, MD Gurbindo… - Clinical infectious …, 2004 - academic.oup.com
An observational study of children vertically infected with human immunodeficiency virus
type 1 (HIV-1) was performed to determine the role of CD38 expression in CD8+ T cells as …

Characterization of HIV-1 subtype C envelope glycoproteins from perinatally infected children with different courses of disease

H Zhang, F Hoffmann, J He, X He, C Kankasa, JT West… - Retrovirology, 2006 - Springer
Background The causal mechanisms of differential disease progression in HIV-1 infected
children remain poorly defined, and much of the accumulated knowledge comes from …

Coreceptor change appears after immune deficiency is established in children infected with different HIV-1 subtypes

C Casper, L Naver, P Clevestig, E Belfrage… - AIDS research and …, 2002 - liebertpub.com
Change of HIV-1 coreceptor use has been connected to progression of disease in children
infected with HIV-1, presumably subtype B. It has not been possible to discern whether the …

Differential HIV-1 replication in neonatal and adult blood mononuclear cells is influenced at the level of HIV-1 gene expression

V Sundaravaradan, SK Saxena… - Proceedings of the …, 2006 - National Acad Sciences
The majority of HIV-1-infected neonates and infants have a higher level of viremia and
develop AIDS more rapidly than infected adults, including differences seen in clinical …