The diverse roles of DNA methylation in mammalian development and disease
MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
DNA methylation is of paramount importance for mammalian embryonic development. DNA
methylation has numerous functions: it is implicated in the repression of transposons and …
methylation has numerous functions: it is implicated in the repression of transposons and …
The epigenetic regulators and metabolic changes in ferroptosis-associated cancer progression
Y Wu, S Zhang, X Gong, S Tam, D Xiao, S Liu, Y Tao - Molecular cancer, 2020 - Springer
Ferroptosis, a novel form of regulated cell death, is different from other types of cell death in
morphology, genetics and biochemistry. Increasing evidence indicates that ferroptosis has …
morphology, genetics and biochemistry. Increasing evidence indicates that ferroptosis has …
Long noncoding RNA LINC00336 inhibits ferroptosis in lung cancer by functioning as a competing endogenous RNA
The regulatory loop between long noncoding RNAs (lncRNAs) and microRNAs has a
dynamic role in transcriptional and translational regulation, and is involved in cancer …
dynamic role in transcriptional and translational regulation, and is involved in cancer …
A nuclear long non-coding RNA LINC00618 accelerates ferroptosis in a manner dependent upon apoptosis
Z Wang, X Chen, N Liu, Y Shi, Y Liu, L Ouyang, S Tam… - Molecular Therapy, 2021 - cell.com
Ferroptosis is primarily caused by intracellular iron catalytic activity and lipid peroxidation.
The potential interplay between ferroptosis and apoptosis remains poorly understood. Here …
The potential interplay between ferroptosis and apoptosis remains poorly understood. Here …
A G3BP1-interacting lncRNA promotes ferroptosis and apoptosis in cancer via nuclear sequestration of p53
Long noncoding RNAs (lncRNA) have been associated with various types of cancer;
however, the precise role of many lncRNAs in tumorigenesis remains elusive. Here we …
however, the precise role of many lncRNAs in tumorigenesis remains elusive. Here we …
[HTML][HTML] The Arabidopsis nucleosome remodeler DDM1 allows DNA methyltransferases to access H1-containing heterochromatin
Nucleosome remodelers of the DDM1/Lsh family are required for DNA methylation of
transposable elements, but the reason for this is unknown. How DDM1 interacts with other …
transposable elements, but the reason for this is unknown. How DDM1 interacts with other …
iDNA4mC: identifying DNA N4-methylcytosine sites based on nucleotide chemical properties
Abstract Motivation DNA N4-methylcytosine (4mC) is an epigenetic modification. The
knowledge about the distribution of 4mC is helpful for understanding its biological functions …
knowledge about the distribution of 4mC is helpful for understanding its biological functions …
[HTML][HTML] EGLN1/c-Myc induced lymphoid-specific helicase inhibits ferroptosis through lipid metabolic gene expression changes
Ferroptosis is a newly discovered form of non-apoptotic cell death in multiple human
diseases. However, the epigenetic mechanisms underlying ferroptosis remain poorly …
diseases. However, the epigenetic mechanisms underlying ferroptosis remain poorly …
De novo DNA methylation: a germ cell perspective
SA Smallwood, G Kelsey - Trends in Genetics, 2012 - cell.com
DNA methylation is a fundamentally important epigenetic modification of the mammalian
genome that has widespread influences on gene expression. During germ-cell specification …
genome that has widespread influences on gene expression. During germ-cell specification …
DNA methylation and differentiation: silencing, upregulation and modulation of gene expression
Differentiation-related DNA methylation is receiving increasing attention, partly owing to
new, whole-genome analyses. These revealed that cell type-specific differential methylation …
new, whole-genome analyses. These revealed that cell type-specific differential methylation …