Cryptococcus neoformans and Cryptococcus gattii are the two etiologic agents of
cryptococcosis. They belong to the phylum Basidiomycota and can be readily distinguished …

Understanding of the taxonomy and phylogeny of Cryptococcus gattii has been advanced by
modern molecular techniques. C. gattii probably diverged from Cryptococcus neoformans …

Metals are essential for life, and they play a central role in the struggle between infecting
microbes and their hosts. In fact, an important aspect of microbial pathogenesis is the …

Calprotectin, a heterodimer of S100A8 and S100A9, is an abundant neutrophil protein that
possesses antimicrobial activity primarily because of its ability to chelate zinc and …

The ability of pathogenic microorganisms to assimilate sufficient nutrients for growth within
their hosts is a fundamental requirement for pathogenicity. However, certain trace nutrients …

Zinc is a ubiquitous metal in all life forms, as it is a structural component of the almost 10% of
eukaryotic proteins, which are called zinc-binding proteins. In zinc-limiting conditions such …

Regular protocols for the isolation of fungal extracellular vesicles (EVs) are time-consuming,
hard to reproduce, and produce low yields. In an attempt to improve the protocols used for …

Zinc-responsive transcription factors are found in all kingdoms of life and include the
transcriptional activators ZntR, SczA, Zap1, bZip19, bZip23, and MTF-1, and transcriptional …

Nutritional immunity describes the host-driven manipulation of essential micronutrients,
including iron, zinc and manganese. To withstand nutritional immunity and proliferate within …

Zinc is an essential nutrient for all organisms because this metal serves as a critical
structural or catalytic cofactor for many proteins. These zinc-dependent proteins are …