Recent advances and new strategies on leishmaniasis treatment
BM Roatt, JM de Oliveira Cardoso… - Applied Microbiology …, 2020 - Springer
Leishmaniasis is one of the most important tropical neglected diseases according to the
World Health Organization. Even after more than a century, we still have few drugs for the …
World Health Organization. Even after more than a century, we still have few drugs for the …
Advancement in leishmaniasis diagnosis and therapeutics: An update
Leishmaniasis is regarded as a neglected tropical disease by World Health Organization
(WHO) and is ranked next to malaria as the deadliest protozoan disease. The primary …
(WHO) and is ranked next to malaria as the deadliest protozoan disease. The primary …
Leishmaniasis immunopathology—impact on design and use of vaccines, diagnostics and drugs
Leishmaniasis is a disease complex caused by 20 species of protozoan parasites belonging
to the genus Leishmania. In humans, it has two main clinical forms, visceral leishmaniasis …
to the genus Leishmania. In humans, it has two main clinical forms, visceral leishmaniasis …
New insights into leishmaniasis in the immunosuppressed
H Akuffo, C Costa, J van Griensven… - PLoS neglected …, 2018 - journals.plos.org
Immunosuppression contributes significantly to the caseload of visceral leishmaniasis (VL).
HIV coinfection, solid organ transplantation, malnutrition, and helminth infections are the …
HIV coinfection, solid organ transplantation, malnutrition, and helminth infections are the …
Current leishmaniasis drug discovery
AC Pinheiro, MVN de Souza - RSC Medicinal Chemistry, 2022 - pubs.rsc.org
Leishmaniasis is a complex protozoan infectious disease and, associated with malnutrition,
poor health services and unavailability of prophylactic control measures, neglected …
poor health services and unavailability of prophylactic control measures, neglected …
[HTML][HTML] Route map for the discovery and pre-clinical development of new drugs and treatments for cutaneous leishmaniasis
D Caridha, B Vesely, K van Bocxlaer, B Arana… - International Journal for …, 2019 - Elsevier
Although there have been significant advances in the treatment of visceral leishmaniasis
(VL) and several novel compounds are currently in pre-clinical and clinical development for …
(VL) and several novel compounds are currently in pre-clinical and clinical development for …
Loop-mediated isothermal amplification as point-of-care diagnosis for neglected parasitic infections
C Avendaño, MA Patarroyo - International Journal of Molecular Sciences, 2020 - mdpi.com
The World Health Organisation (WHO) has placed twenty diseases into a group known as
neglected tropical diseases (NTDs), twelve of them being parasitic diseases: Chagas' …
neglected tropical diseases (NTDs), twelve of them being parasitic diseases: Chagas' …
The Therapeutic Effects of Curcumin-coated Gold Nanoparticle Against Leishmania Major Causative Agent of Zoonotic Cutaneous Leishmaniasis (ZCL): An In Vitro …
We synthesized and characterized curcumin-coated gold nanoparticles (Cur@ AuNPs) and
investigated their stability, cytotoxicity, leishmanicidal activity in in vitro and in in vivo …
investigated their stability, cytotoxicity, leishmanicidal activity in in vitro and in in vivo …
Immunotherapy in treatment of leishmaniasis
Leishmaniasis caused by various species of protozoan transmitted by sand fly vectors
occurs as a spectrum of clinical features including cutaneous, mucocutaneous and visceral …
occurs as a spectrum of clinical features including cutaneous, mucocutaneous and visceral …
Centrin-deficient Leishmania mexicana confers protection against Old World visceral leishmaniasis
S Karmakar, G Volpedo, WW Zhang, P Lypaczewski… - npj Vaccines, 2022 - nature.com
Leishmaniasis is one of the top neglected tropical diseases with significant morbidity and
mortality in low and middle-income countries (LMIC). However, this disease is also …
mortality in low and middle-income countries (LMIC). However, this disease is also …