Fluorescent dyes based on rhodamine derivatives for bioimaging and therapeutics: recent progress, challenges, and prospects

S Zeng, X Liu, YS Kafuti, H Kim, J Wang… - Chemical Society …, 2023 - pubs.rsc.org
Since their inception, rhodamine dyes have been extensively applied in biotechnology as
fluorescent markers or for the detection of biomolecules owing to their good optical physical …

Intracellular delivery by membrane disruption: mechanisms, strategies, and concepts

MP Stewart, R Langer, KF Jensen - Chemical reviews, 2018 - ACS Publications
Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …

Zinc oxide nanoparticles: A comprehensive review on its synthesis, anticancer and drug delivery applications as well as health risks

TA Singh, J Das, PC Sil - Advances in colloid and interface science, 2020 - Elsevier
In recent years, zinc oxide nanoparticles (ZnONPs) emerged as an excellent candidate in
the field of optical, electrical, food packaging and particularly in biomedical research …

Brief update on endocytosis of nanomedicines

S Patel, J Kim, M Herrera, A Mukherjee… - Advanced drug delivery …, 2019 - Elsevier
The complexity of nanoscale interactions between biomaterials and cells has limited the
realization of the ultimate vision of nanotechnology in diagnostics and therapeutics. As such …

Visualization of the process of a nanocarrier-mediated gene delivery: stabilization, endocytosis and endosomal escape of genes for intracellular spreading

Z Ma, Y Zheng, Z Chao, H Chen, Y Zhang… - Journal of …, 2022 - Springer
Nanoparticles have been widely applied as gene carrier for improving RNA interference
(RNAi) efficiency in medical and agricultural fields. However, the mechanism and delivery …

Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth

SE Kim, L Zhang, K Ma, M Riegman, F Chen… - Nature …, 2016 - nature.com
The design of cancer-targeting particles with precisely tuned physicochemical properties
may enhance the delivery of therapeutics and access to pharmacological targets. However …

Fluorescent polymer nanoparticles based on dyes: seeking brighter tools for bioimaging

A Reisch, AS Klymchenko - Small, 2016 - Wiley Online Library
Speed, resolution and sensitivity of today's fluorescence bioimaging can be drastically
improved by fluorescent nanoparticles (NPs) that are many‐fold brighter than organic dyes …

Insight into nanoparticle cellular uptake and intracellular targeting

B Yameen, WI Choi, C Vilos, A Swami, J Shi… - Journal of controlled …, 2014 - Elsevier
Collaborative efforts from the fields of biology, materials science, and engineering are
leading to exciting progress in the development of nanomedicines. Since the targets of many …

Nucleic acid therapeutics using polyplexes: a journey of 50 years (and beyond)

U Lächelt, E Wagner - Chemical reviews, 2015 - ACS Publications
Since the elucidation of the molecular structure of nucleic acids and understanding of their
role in encoding and translating genetic information into biological function, 1 the knowledge …

Curcumin nanoformulations: a review of pharmaceutical properties and preclinical studies and clinical data related to cancer treatment

O Naksuriya, S Okonogi, RM Schiffelers, WE Hennink - Biomaterials, 2014 - Elsevier
Curcumin, a natural yellow phenolic compound, is present in many kinds of herbs,
particularly in Curcuma longa Linn.(turmeric). It is a natural antioxidant and has shown many …