[HTML][HTML] Multimodal experimental studies of the passive mechanical behavior of human aortas: current approaches and future directions
Cardiovascular diseases are the leading cause of death worldwide and include, among
others, critical conditions of the aortic wall. Importantly, such critical conditions require …
others, critical conditions of the aortic wall. Importantly, such critical conditions require …
[HTML][HTML] Multiscale computational modeling of arterial micromechanics: A review
M Dalbosco, EA Fancello, GA Holzapfel - Computer Methods in Applied …, 2024 - Elsevier
The mechanical properties of arterial tissue play a central role in healthy human physiology
and have therefore been extensively studied and modeled in recent decades. These …
and have therefore been extensively studied and modeled in recent decades. These …
Histology-informed multiscale modeling of human brain white matter
In this study, we propose a novel micromechanical model for the brain white matter, which is
described as a heterogeneous material with a complex network of axon fibers embedded in …
described as a heterogeneous material with a complex network of axon fibers embedded in …
[HTML][HTML] Changes in the microstructure of the human aortic adventitia under biaxial loading investigated by multi-photon microscopy
A Pukaluk, H Wolinski, C Viertler, P Regitnig… - Acta Biomaterialia, 2023 - Elsevier
Among the three layers of the aortic wall, the media is primarily responsible for its
mechanical properties, but the adventitia prevents the aorta from overstretching and …
mechanical properties, but the adventitia prevents the aorta from overstretching and …
A two-scale numerical study on the mechanobiology of abdominal aortic aneurysms
M Dalbosco, M Terzano, TA Carniel… - Journal of the …, 2023 - royalsocietypublishing.org
Abdominal aortic aneurysms (AAAs) are a serious condition whose pathophysiology is
related to phenomena occurring at different length scales. To gain a better understanding of …
related to phenomena occurring at different length scales. To gain a better understanding of …
Differences in collagen fiber diameter and waviness between healthy and aneurysmal abdominal aortas
Collagen plays a key role in the strength of aortic walls, so studying micro-structural changes
during disease development is critical to better understand collagen reorganization. Second …
during disease development is critical to better understand collagen reorganization. Second …
Compressive failure analysis of in-situ Al-Mg2Si composites: Experiment and finite element modelling
Abstract Al-Mg 2 Si composites have been developed through gravity die-casting
techniques. The influence of Mg 2 Si reinforcement concentration on strength …
techniques. The influence of Mg 2 Si reinforcement concentration on strength …
Unified three-dimensional finite elements for large strain analysis of compressible and nearly incompressible solids
This work proposes a displacement-based finite element model for large strain analysis of
isotropic compressible and nearly-incompressible hyperelastic materials. Constitutive law is …
isotropic compressible and nearly-incompressible hyperelastic materials. Constitutive law is …
[HTML][HTML] Changes in the microstructure of the human aortic medial layer under biaxial loading investigated by multi-photon microscopy
A Pukaluk, H Wolinski, C Viertler, P Regitnig… - Acta Biomaterialia, 2022 - Elsevier
Understanding the correlation between tissue architecture, health status, and mechanical
properties is essential for improving material models and developing tissue engineering …
properties is essential for improving material models and developing tissue engineering …
[HTML][HTML] On the descriptive and predictive capabilities of two model approaches considering the collagen fiber dispersion in healthy and aneurysmal arteries
DC Haspinger, GA Holzapfel - European Journal of Mechanics-A/Solids, 2023 - Elsevier
Most constitutive models aim to describe the arterial macroscopic mechanical behavior via
an elastin-rich ground substance reinforced by spatially dispersed collagen fibers. Two …
an elastin-rich ground substance reinforced by spatially dispersed collagen fibers. Two …