Early Life Stress Affects Bdnf Regulation: A Role for Exercise Interventions

TS Campbell, KM Donoghue, U Ghosh… - International Journal of …, 2022 - mdpi.com
Early life stress (ELS) encompasses exposure to aversive experiences during early
development, such as neglect or maltreatment. Animal and human studies indicate that ELS …

[HTML][HTML] Beneficial effects of physical exercise on cognitive-behavioral impairments and brain-derived neurotrophic factor alteration in the limbic system induced by …

F Sanaeifar, S Pourranjbar, M Pourranjbar… - Experimental …, 2024 - Elsevier
Neurodegenerative diseases (NDDs) are a class of neurological disorders marked by the
progressive loss of neurons that afflict millions of people worldwide. These illnesses affect …

GALR2 and Y1R agonists intranasal infusion enhanced adult ventral hippocampal neurogenesis and antidepressant‐like effects involving BDNF actions

JE Alvarez‐Contino, E Díaz‐Sánchez… - Journal of Cellular …, 2023 - Wiley Online Library
Dysregulation of adult hippocampal neurogenesis is linked to major depressive disorder
(MDD), with more than 300 million people diagnosed and worsened by the COVID‐19 …

Antidepressive effect of natural products and their derivatives targeting BDNF-TrkB in gut–brain axis

H Liaqat, A Parveen, SY Kim - International journal of molecular sciences, 2022 - mdpi.com
Modern neurological approaches enable detailed studies on the pathophysiology and
treatment of depression. An imbalance in the microbiota–gut–brain axis contributes to the …

Role of brain renin–angiotensin system in depression: a new perspective

NH Ali, HM Al‐Kuraishy, AI Al‐Gareeb… - CNS Neuroscience …, 2024 - Wiley Online Library
Depression is a mood disorder characterized by abnormal thoughts. The pathophysiology of
depression is related to the deficiency of serotonin (5HT), which is derived from tryptophan …

Major Depressive Disorder and Gut Microbiota: Role of Physical Exercise

PB Souza, L de Araujo Borba… - International journal of …, 2023 - mdpi.com
Major depressive disorder (MDD) has a high prevalence and is a major contributor to the
global burden of disease. This psychiatric disorder results from a complex interaction …

BDNF unveiled: exploring its role in major depression disorder serotonergic imbalance and associated stress conditions

AS Correia, A Cardoso, N Vale - Pharmaceutics, 2023 - mdpi.com
Brain-derived neurotrophic factor (BDNF) is a neurotrophin that plays a significant role in the
survival and development of neurons, being involved in several diseases such as …

A novel epithelial–mesenchymal transition gene signature for the immune status and prognosis of hepatocellular carcinoma

Y Shi, J Wang, G Huang, J Zhu, H Jian, G Xia… - Hepatology …, 2022 - Springer
Background This study clarified whether EMT-related genes can predict immunotherapy
efficacy and overall survival in patients with HCC. Methods The RNA-sequencing profiles …

The effects of chronic unpredictable mild stress and semi-pure diets on the brain, gut and adrenal medulla in C57BL6 mice

MF Herselman, L Bobrovskaya - International Journal of Molecular …, 2023 - mdpi.com
Chronic stress is known to perturb serotonergic regulation in the brain, leading to mood,
learning and memory impairments and increasing the risk of developing mood disorders …

The effects of physical activity interventions on self-esteem during and after cancer treatment: a systematic review and meta-analysis

A Rodriguez-Solana, L Gracia-Marco… - Scientific Reports, 2024 - nature.com
To investigate the effect of physical activity (PA)(both general and its type) on self-esteem
during and after cancer treatment. A systematic search was conducted across PubMed, Web …