Sperm DNA integrity is crucial for fertilization and development of healthy offspring. The
spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases …

Oxidative stress is an important factor for development of male infertility because of very high
rate of cell division and mitochondrial oxygen consumption in testicular tissue as well as …

The human genome is generally organized into stable chromosomes, and only tumor cells
are known to accumulate kilobase (kb)-sized extrachromosomal circular DNA elements …

DNA fragmentation is an important factor in the aetiology of male infertility. However, it is still
underevaluated and its inclusion in routine semen analysis is debated. DNA fragmentation …

Oxidative stress occurs when the production of potentially destructive reactive oxygen
species (ROS) exceeds the bodies own natural antioxidant defenses, resulting in cellular …

Spermatogenesis is an extremely active replicative process capable of generating approxi
mately 1,000 sperm a second. The high rates of cell division inherent in this process imply …

Sperm cryopreservation is a powerful tool for the livestock breeding program. Several
technical attempts have been made to enhance the efficiency of spermatozoa …

The male factor is considered a major contributory factor to infertility. Apart from the
conventional causes for male infertility such as varicocoele, cryptorchidism, infections …

Oxidative stress results from the production of oxygen radicals in excess of the antioxidant
capacity of the stressed tissue. Many conditions or events associated with male infertility are …

Varicocele, a cause of male infertility, occurs in nearly 40% of infertile males. It has been
postulated that varicoceles may cause sperm DNA damage. Sperm DNA integrity has been …