Emerging nanotechnology and advanced materials for cancer radiation therapy
Radiation therapy (RT) including external beam radiotherapy (EBRT) and internal
radioisotope therapy (RIT) has been widely used for clinical cancer treatment. However …
radioisotope therapy (RIT) has been widely used for clinical cancer treatment. However …
Nanomedicines accessible in the market for clinical interventions
V Gadekar, Y Borade, S Kannaujia, K Rajpoot… - Journal of Controlled …, 2021 - Elsevier
Nanomedicines refers to nanotechnology inspired pharmaceutical products often referred to
as 'nanopharmaceuticals.'It has displayed commendable potential in enhancing therapeutic …
as 'nanopharmaceuticals.'It has displayed commendable potential in enhancing therapeutic …
The Warburg effect and glucose-derived cancer theranostics
RK Tekade, X Sun - Drug Discovery Today, 2017 - Elsevier
Highlights•Tumor cells increase their metabolic rates as well as glucose uptake to maintain
amplified proliferation,•Consequently, tumor cells switch from mitochondrial oxidative …
amplified proliferation,•Consequently, tumor cells switch from mitochondrial oxidative …
Reactive oxygen nano-generators for cancer therapy
Reactive oxygen species (ROS) play a vital role in the biological process. Interestingly,
based on the concentration of the ROS level, they can be beneficial or detrimental to tumor …
based on the concentration of the ROS level, they can be beneficial or detrimental to tumor …
Pharmacokinetic and pharmacodynamic features of nanoemulsion following oral, intravenous, topical and nasal route
Background: Most of the active pharmaceutical ingredients discovered recently in
pharmaceutical field exhibits poor aqueous solubility that pose major problem in their oral …
pharmaceutical field exhibits poor aqueous solubility that pose major problem in their oral …
Molecular dynamics simulation strategies for designing carbon-nanotube-based targeted drug delivery
Highlights•CNT-based target-specific drug delivery is a promising approach to circumvent
the limitations of nonspecific therapeutic agents.•Interactions between the drug, CNT and …
the limitations of nonspecific therapeutic agents.•Interactions between the drug, CNT and …
[HTML][HTML] Main approaches to enhance radiosensitization in cancer cells by nanoparticles: A systematic review
In recent years, high atomic number nanoparticles (NPs) have emerged as promising radio-
enhancer agents for cancer radiation therapy due to their unique properties. Multi …
enhancer agents for cancer radiation therapy due to their unique properties. Multi …
Nanomaterials assisted chemo-photothermal therapy for combating cancer drug resistance
Chemoresistance is the refractoriness of the cancer cells to the commonly used
chemotherapeutic agents. It is one of the significant challenges in the treatment of cancer. To …
chemotherapeutic agents. It is one of the significant challenges in the treatment of cancer. To …
RNAi-combined nano-chemotherapeutics to tackle resistant tumors
RK Tekade, M Tekade, P Kesharwani… - Drug discovery today, 2016 - Elsevier
Highlights•Nanotechnology can protect siRNA against RNAse degradation.•siRNA adopts
an alternative pathway to knock genes with high specificity to cure cancer.•An ideal vector is …
an alternative pathway to knock genes with high specificity to cure cancer.•An ideal vector is …
Lyophilized mucoadhesive-dendrimer enclosed matrix tablet for extended oral delivery of albendazole
S Mansuri, P Kesharwani, RK Tekade… - European Journal of …, 2016 - Elsevier
Dendrimers are multifunctional carriers widely employed for delivering drugs in a variety of
disease conditions including HIV/AIDS and cancer. Albendazole (ABZ) is a commonly used …
disease conditions including HIV/AIDS and cancer. Albendazole (ABZ) is a commonly used …