Emerging nanotechnology and advanced materials for cancer radiation therapy

G Song, L Cheng, Y Chao, K Yang, Z Liu - Advanced materials, 2017 - Wiley Online Library
Radiation therapy (RT) including external beam radiotherapy (EBRT) and internal
radioisotope therapy (RIT) has been widely used for clinical cancer treatment. However …

Nanomedicines accessible in the market for clinical interventions

V Gadekar, Y Borade, S Kannaujia, K Rajpoot… - Journal of Controlled …, 2021 - Elsevier
Nanomedicines refers to nanotechnology inspired pharmaceutical products often referred to
as 'nanopharmaceuticals.'It has displayed commendable potential in enhancing therapeutic …

The Warburg effect and glucose-derived cancer theranostics

RK Tekade, X Sun - Drug Discovery Today, 2017 - Elsevier
Highlights•Tumor cells increase their metabolic rates as well as glucose uptake to maintain
amplified proliferation,•Consequently, tumor cells switch from mitochondrial oxidative …

Reactive oxygen nano-generators for cancer therapy

D Kalyane, D Choudhary, S Polaka, H Goykar… - Progress in Materials …, 2022 - Elsevier
Reactive oxygen species (ROS) play a vital role in the biological process. Interestingly,
based on the concentration of the ROS level, they can be beneficial or detrimental to tumor …

Pharmacokinetic and pharmacodynamic features of nanoemulsion following oral, intravenous, topical and nasal route

H Choudhury, B Gorain, B Chatterjee… - Current …, 2017 - benthamdirect.com
Background: Most of the active pharmaceutical ingredients discovered recently in
pharmaceutical field exhibits poor aqueous solubility that pose major problem in their oral …

Molecular dynamics simulation strategies for designing carbon-nanotube-based targeted drug delivery

MN Al-Qattan, PK Deb, RK Tekade - Drug discovery today, 2018 - Elsevier
Highlights•CNT-based target-specific drug delivery is a promising approach to circumvent
the limitations of nonspecific therapeutic agents.•Interactions between the drug, CNT and …

[HTML][HTML] Main approaches to enhance radiosensitization in cancer cells by nanoparticles: A systematic review

BB Abdollahi, R Malekzadeh, FP Azar… - Advanced …, 2020 - pmc.ncbi.nlm.nih.gov
In recent years, high atomic number nanoparticles (NPs) have emerged as promising radio-
enhancer agents for cancer radiation therapy due to their unique properties. Multi …

Nanomaterials assisted chemo-photothermal therapy for combating cancer drug resistance

V Patel, C Rajani, V Tambe, D Kalyane, N Anup… - Journal of Drug Delivery …, 2022 - Elsevier
Chemoresistance is the refractoriness of the cancer cells to the commonly used
chemotherapeutic agents. It is one of the significant challenges in the treatment of cancer. To …

RNAi-combined nano-chemotherapeutics to tackle resistant tumors

RK Tekade, M Tekade, P Kesharwani… - Drug discovery today, 2016 - Elsevier
Highlights•Nanotechnology can protect siRNA against RNAse degradation.•siRNA adopts
an alternative pathway to knock genes with high specificity to cure cancer.•An ideal vector is …

Lyophilized mucoadhesive-dendrimer enclosed matrix tablet for extended oral delivery of albendazole

S Mansuri, P Kesharwani, RK Tekade… - European Journal of …, 2016 - Elsevier
Dendrimers are multifunctional carriers widely employed for delivering drugs in a variety of
disease conditions including HIV/AIDS and cancer. Albendazole (ABZ) is a commonly used …