The global burden of neurodegenerative disorders has increased substantially over the past
2 decades due to rising rates of population aging. Although neurodegenerative disorders …

Curcumin, used as a spice and traditional medicine in India, exerts beneficial effects against
several diseases, owing to its antioxidant, analgesic, and anti-inflammatory properties …

Accumulating evidence has demonstrated that oxidative stress is associated with
depression. Our present study aimed at investigating the antidepressant effect and the …

The present study was performed to investigate the antidepressant effect of echinacoside
(ECH) using chronic unpredictable mild stress (CUMS) induced depression mice and …

Background Methamphetamine is a neuro-stimulant with neurodegenerative effects, and
ambiguous mechanism of action. Metformin is an antidiabetic agent with neuroprotective …

Introduction: Memory is defined as the ability to store, maintain and retrieve information.
Learning is the acquisition of information that changes behavior and memory. Stress …

Curcumin is an anti-inflammatory and antioxidant compound with potent neuroprotective
activity. Due to its poor water solubility, low bioavailability, rapid elimination and the …

Background Doxorubicin (DOX)-induced neurotoxicity is widely reported in previous studies.
Oxidative stress has been validated as a critical event involved in DOX-induced …

Abstract Background and Purpose Curcumin, a natural antioxidant isolated from Curcuma
longa, has been reported to exert neuroprotective effect in animal models of ischemic stroke …

Neurodegenerative diseases are disabling chronic disorders characterized by the
progressive loss of neurons in different areas of the central nervous system …