Autism spectrum disorders (ASD) are pervasive neurodevelopmental disorders that include
a variety of forms and clinical phenotypes. This heterogeneity complicates the clinical and …

Adenosine exerts an important role in the modulation of central nervous system (CNS)
activity. Through the interaction with four G-protein coupled receptor (GPCR) subtypes …

Exosomes, nanovesicles that are secreted by different cell types, enable intercellular
communication at local or distant sites. Alhough they have been found to cross the blood …

Folic acid (FA)-induced renal tubule damage, which is characterized by extensive
inflammation, is a common model of acute kidney injury (AKI). Pyroptosis, a pro …

Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder with few
pharmacological treatments. Minocycline, a tetracycline derivative that inhibits microglial …

Autism spectrum disorder (ASD) is a complicated, heterogeneous disorder characterized by
social interaction deficits and repetitive stereotypical behaviors. Neuroinflammation and …

The recent outbreak of the Zika virus (ZIKV) and the discovery that perinatal Zika exposure
can lead to the Congenital Zika Syndrome has promoted a call for prevention measures …

Heart failure is typically caused by different cardiovascular conditions and has a poor
prognosis. Despite the advances in treatment in recent decades, heart failure has remained …

Background Autism is a clinically defined neurodevelopmental disorder with unknown origin
characterized by significant social, communication and behavioral challenges. Although it …

Dry eye disease (DED) is a complex ocular surface inflammatory disease. Its occurrence
varies widely over the world, ranging from 5% to 34%. The use of preservatives, specifically …