Cytomegalovirus infection during pregnancy: state of the science

M Leruez-Ville, I Foulon, R Pass, Y Ville - American journal of obstetrics and …, 2020 - Elsevier
Cytomegalovirus is the most common congenital infection, affecting 0.5–2% of all live births
and the main nongenetic cause of congenital sensorineural hearing loss and neurological …

Consequences of viral infection and cytokine production during pregnancy on brain development in offspring

D Elgueta, P Murgas, E Riquelme, G Yang… - Frontiers in …, 2022 - frontiersin.org
Infections during pregnancy can seriously damage fetal neurodevelopment by aberrantly
activating the maternal immune system, directly impacting fetal neural cells. Increasing …

[HTML][HTML] Human virus transcriptional regulators

X Liu, T Hong, S Parameswaran, K Ernst, I Marazzi… - Cell, 2020 - cell.com
Viral genomes encode transcriptional regulators that alter the expression of viral and host
genes. Despite an emerging role in human diseases, a thorough annotation of human viral …

Congenital human cytomegalovirus infection and neurologic diseases in newborns

XY Zhang, F Fang - Chinese Medical Journal, 2019 - mednexus.org
Objective: This review aimed to summarize research progress regarding congenital
cytomegalovirus (cCMV) infection-related nervous system diseases and their mechanisms …

Fetal brain damage in human fetuses with congenital cytomegalovirus infection: histological features and viral tropism

G Piccirilli, L Gabrielli, MP Bonasoni… - Cellular and Molecular …, 2023 - Springer
Human cytomegalovirus (HCMV) causes congenital neurological lifelong disabilities. To
date, the neuropathogenesis of brain injury related to congenital HCMV (cCMV) infection is …

Congenital cytomegalovirus infection: the state of the art and future perspectives

S Salomè, FR Corrado, LL Mazzarelli… - Frontiers in …, 2023 - frontiersin.org
Congenital cytomegalovirus (cCMV) infection is the most common congenital infection, with
an estimated incidence of approximately one in 200 infants in high-income settings …

Association of cytomegalovirus and toxoplasma gondii antibody titers with bipolar disorder

MA Frye, BJ Coombes, SL McElroy… - JAMA …, 2019 - jamanetwork.com
Importance Infection-associated immune activation and inflammation are increasingly
recognized in the pathophysiology of bipolar disorder. Objective To determine whether …

PPAR gamma and viral infections of the brain

P Layrolle, P Payoux, S Chavanas - International journal of molecular …, 2021 - mdpi.com
Peroxisome Proliferator-Activated Receptor gamma (PPARγ) is a master regulator of
metabolism, adipogenesis, inflammation and cell cycle, and it has been extensively studied …

Changes in ADAR RNA editing patterns in CMV and ZIKV congenital infections

B Wales-McGrath, H Mercer, H Piontkivska - BMC genomics, 2023 - Springer
Background RNA editing is a process that increases transcriptome diversity, often through
Adenosine Deaminases Acting on RNA (ADARs) that catalyze the deamination of …

Human cytomegalovirus infection is associated with increased expression of the lissencephaly gene PAFAH1B1 encoding LIS1 in neural stem cells and congenitally …

M Rolland, H Martin, M Bergamelli… - The Journal of …, 2021 - Wiley Online Library
Congenital infection of the central nervous system by human cytomegalovirus (HCMV) is a
leading cause of permanent sequelae, including mental retardation or neurodevelopmental …