Chemistry of MRI contrast agents: current challenges and new frontiers
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …
performed annually around the world. The contrast agents, which improve diagnostic …
[HTML][HTML] European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)
Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …
Activatable Fluorescence/MRI Bimodal Platform for Tumor Cell Imaging via MnO2 Nanosheet–Aptamer Nanoprobe
Z Zhao, H Fan, G Zhou, H Bai, H Liang… - Journal of the …, 2014 - ACS Publications
A novel dual-activatable fluorescence/MRI bimodal platform is designed for tumor cell
imaging by using a redoxable manganese dioxide (MnO2) nanosheet–aptamer nanoprobe …
imaging by using a redoxable manganese dioxide (MnO2) nanosheet–aptamer nanoprobe …
A review of responsive MRI contrast agents: 2005–2014
DV Hingorani, AS Bernstein… - Contrast media & …, 2015 - Wiley Online Library
This review focuses on MRI contrast agents that are responsive to a change in a
physiological biomarker. The response mechanisms are dependent on six physicochemical …
physiological biomarker. The response mechanisms are dependent on six physicochemical …
Applications for transition-metal chemistry in contrast-enhanced magnetic resonance imaging
Contrast-enhanced magnetic resonance imaging (MRI) is an indispensable tool for
diagnostic medicine. However, safety concerns related to gadolinium in commercial MRI …
diagnostic medicine. However, safety concerns related to gadolinium in commercial MRI …
Mn-based MRI contrast agents: an overview
C Henoumont, M Devreux, S Laurent - Molecules, 2023 - mdpi.com
MRI contrast agents are required in the clinic to detect some pathologies, such as cancers.
Nevertheless, at the moment, only small extracellular and non-specific gadolinium …
Nevertheless, at the moment, only small extracellular and non-specific gadolinium …
Rationally designed mimics of antioxidant manganoenzymes: Role of structural features in the quest for catalysts with catalase and superoxide dismutase activity
S Signorella, C Palopoli, G Ledesma - Coordination Chemistry Reviews, 2018 - Elsevier
Manganese catalases (MnCAT) and superoxide dismutases (MnSOD) deplete hydrogen
peroxide and superoxide in cells through a ping-pong mechanism involving cyclic oxidation …
peroxide and superoxide in cells through a ping-pong mechanism involving cyclic oxidation …
Advances in gadolinium-based MRI contrast agent designs for monitoring biological processes in vivo
Highlights•Responsive MRI agents provide new insights into Zn 2+ ion release from
secretory tissues.•Small molecule targeted agents are sensitive enough to detect abundant …
secretory tissues.•Small molecule targeted agents are sensitive enough to detect abundant …
Metal-based redox-responsive MRI contrast agents
SM Pinto, V Tomé, MJF Calvete, MMCA Castro… - Coordination Chemistry …, 2019 - Elsevier
Given their potential in a better characterization and diagnosis of major pathologies like
cancer or chronic inflammation, redox-activated Magnetic Resonance Imaging (MRI) probes …
cancer or chronic inflammation, redox-activated Magnetic Resonance Imaging (MRI) probes …
Direct Measurement of the Mn(II) Hydration State in Metal Complexes and Metalloproteins through 17O NMR Line Widths
Here we describe a simple method to estimate the inner-sphere hydration state of the Mn (II)
ion in coordination complexes and metalloproteins. The line width of bulk H217O is …
ion in coordination complexes and metalloproteins. The line width of bulk H217O is …