Valproic Acid in Pregnancy Revisited: Neurobehavioral, Biochemical and Molecular Changes Affecting the Embryo and Fetus in Humans and in Animals: A Narrative …
Valproic acid (VPA) is a very effective anticonvulsant and mood stabilizer with relatively few
side effects. Being an epigenetic modulator, it undergoes clinical trials for the treatment of …
side effects. Being an epigenetic modulator, it undergoes clinical trials for the treatment of …
Applications for Deep Learning in Epilepsy Genetic Research
R Zeibich, P Kwan, T J. O'Brien, P Perucca… - International journal of …, 2023 - mdpi.com
Epilepsy is a group of brain disorders characterised by an enduring predisposition to
generate unprovoked seizures. Fuelled by advances in sequencing technologies and …
generate unprovoked seizures. Fuelled by advances in sequencing technologies and …
Valproic acid-induced teratogenicity is driven by senescence and prevented by Rapamycin in human spinal cord and animal models
Valproic acid (VPA) is an effective and widely used anti-seizure medication but is
teratogenic when used during pregnancy, affecting brain and spinal cord development for …
teratogenic when used during pregnancy, affecting brain and spinal cord development for …
Enhancing social behavior in an autism spectrum disorder mouse model: investigating the underlying mechanisms of Lactiplantibacillus plantarum intervention
CM Chen, CC Wu, Y Kim, WY Hsu, YC Tsai… - Gut Microbes, 2024 - Taylor & Francis
Autism spectrum disorder (ASD) is a neurodevelopmental disorder affecting over 1% of the
global population. Individuals with ASD often exhibit complex behavioral conditions …
global population. Individuals with ASD often exhibit complex behavioral conditions …
[HTML][HTML] Sex-biased single-cell genetic landscape in mice with autism spectrum disorder
Q Zhang, Y Wang, J Tao, R Xia, Y Zhang, Z Liu… - Journal of Genetics and …, 2024 - Elsevier
Autistic spectrum disorder (ASD) is a male-biased, heterogeneous neurodevelopmental
disorder that affects approximately 1%–2% of the population. Prenatal exposure to valproic …
disorder that affects approximately 1%–2% of the population. Prenatal exposure to valproic …
Effects of co‐administration of lamotrigine on valproate transfer across the placenta and its brain entry in developing Genetic Absence Epilepsy Rats from Strasbourg …
F Qiu, Y Huang, KM Dziegielewska… - European Journal of …, 2024 - Wiley Online Library
During development, embryos and foetuses may be exposed to maternally ingested
antiseizure medications (ASM), valproate and lamotrigine, essential in some patients to …
antiseizure medications (ASM), valproate and lamotrigine, essential in some patients to …
How does foetal exposure to valproate produce adverse neurodevelopmental outcomes?
How does foetal exposure to valproate produce adverse neurodevelopmental outcomes? |
Brain | Oxford Academic Skip to Main Content Advertisement Oxford Academic Journals …
Brain | Oxford Academic Skip to Main Content Advertisement Oxford Academic Journals …
Rapamycin mitigates Valproic Acid-induced teratogenicity in human and animal models by suppressing AP-1-mediated senescence
Valproic acid (VPA) is an effective and widely used anti-seizure medication but is
teratogenic when used during pregnancy, affecting brain and spinal cord development for …
teratogenic when used during pregnancy, affecting brain and spinal cord development for …
Prenatal valproic acid on the basis of gestational diabetes also induces autistic behavior and disrupts myelination and oligodendroglial maturation slightly in offspring
J Zhou, M Li, Z Qiao, J Li, H Zhou, D Huang, Y Cain… - 2024 - researchsquare.com
Gestational diabetes mellitus (GDM) and prenatal exposure to valproic acid (VPA) are both
constitute risk factors for autism in progeny. Notably, dysmyelination in the corpus callosum …
constitute risk factors for autism in progeny. Notably, dysmyelination in the corpus callosum …
[PDF][PDF] Evaluating Disorders of Cognition Using Integrative Genomics
R Feleke - 2023 - core.ac.uk
Integrative genomics embodies a collaborative approach that brings together various
disciplines, merging genomic and computational methodologies to achieve a …
disciplines, merging genomic and computational methodologies to achieve a …