Nitric oxide/nitric oxide synthase system in the pathogenesis of neurodegenerative disorders—an overview

OM Iova, GE Marin, I Lazar, I Stanescu, G Dogaru… - Antioxidants, 2023 - mdpi.com
Nitric oxide, a ubiquitous molecule found throughout the natural world, is a key molecule
implicated in many central and benefic molecular pathways and has a well-established role …

Looking back at the early stages of redox biology

L Flohé - Antioxidants, 2020 - mdpi.com
The beginnings of redox biology are recalled with special emphasis on formation,
metabolism and function of reactive oxygen and nitrogen species in mammalian systems …

[HTML][HTML] Endothelial nitric oxide synthase (eNOS) and the cardiovascular system: in physiology and in disease states

N Tran, T Garcia, M Aniqa, S Ali, A Ally… - American journal of …, 2022 - ncbi.nlm.nih.gov
Endothelial nitric oxide synthase (eNOS) plays a critical role in regulating and maintaining a
healthy cardiovascular system. The importance of eNOS can be emphasized from the …

Effects of disorders in interdependent calcium and IP3 dynamics on nitric oxide production in a neuron cell

A Pawar, K Raj Pardasani - The European Physical Journal Plus, 2022 - Springer
Abstract Calcium ([Ca 2+]), IP 3, and nitric oxide (NO) play a significant role in cell signaling
to maintain various physiological functions. Calcium and IP 3 regulation has been …

Study of disorders in regulatory spatiotemporal neurodynamics of calcium and nitric oxide

A Pawar, KR Pardasani - Cognitive Neurodynamics, 2023 - Springer
Experimental studies have reported the dependence of nitric oxide (NO) on the regulation of
neuronal calcium ([Ca2+]) dynamics in neurons. But, there is no model available to estimate …

Dysfunctional and dysregulated nitric oxide synthases in cardiovascular disease: mechanisms and therapeutic potential

R Roy, J Wilcox, AJ Webb, K O'Gallagher - International journal of …, 2023 - mdpi.com
Nitric oxide (NO) plays an important and diverse signalling role in the cardiovascular system,
contributing to the regulation of vascular tone, endothelial function, myocardial function …

Plant polyphenols: potential antidotes for lead exposure

Y Li, H Lv, C Xue, N Dong, C Bi, A Shan - Biological trace element …, 2021 - Springer
Lead is one of the most common heavy metal elements and has high biological toxicity.
Long-term lead exposure will induce the contamination of animal feed, water, and food …

Modelling Cross Talk in the Spatiotemporal System Dynamics of Calcium, IP3 and Nitric Oxide in Neuron Cells

A Pawar, KR Pardasani - Cell Biochemistry and Biophysics, 2024 - Springer
The bioenergetic system of calcium ([Ca2+]), inositol 1, 4, 5-trisphophate (IP3) and nitric
oxide (NO) regulate the diverse mechanisms in neurons. The dysregulation in any or all of …

[HTML][HTML] Oridonin attenuates lung inflammation and fibrosis in silicosis via covalent targeting iNOS

J Gao, C Li, X Wang, X Sun, R Zhang, M Yu… - Biomedicine & …, 2022 - Elsevier
Silicosis, the most common type of pneumoconiosis, exhibits a high incidence in workers
who are chronically exposed to crystalline silica (CS). No specific remedy for cure as yet …

Methylene blue application to lessen pain: its analgesic effect and mechanism

SW Lee, HC Han - Frontiers in Neuroscience, 2021 - frontiersin.org
Methylene blue (MB) is a cationic thiazine dye, widely used as a biological stain and
chemical indicator. Growing evidence have revealed that MB functions to restore abnormal …