HIV-1 drug resistance before initiation or re-initiation of first-line antiretroviral therapy in low-income and middle-income countries: a systematic review and meta …

RK Gupta, J Gregson, N Parkin… - The Lancet infectious …, 2018 - thelancet.com
Background Pretreatment drug resistance in people initiating or re-initiating antiretroviral
therapy (ART) containing non-nucleoside reverse transcriptase inhibitors (NNRTIs) might …

HIV-1 drug resistance and resistance testing

DS Clutter, MR Jordan, S Bertagnolio… - Infection, Genetics and …, 2016 - Elsevier
The global scale-up of antiretroviral (ARV) therapy (ART) has led to dramatic reductions in
HIV-1 mortality and incidence. However, HIV drug resistance (HIVDR) poses a potential …

Point-of-care nucleic acid testing for infectious diseases

A Niemz, TM Ferguson, DS Boyle - Trends in biotechnology, 2011 - cell.com
Nucleic acid testing for infectious diseases at the point of care is beginning to enter clinical
practice in developed and developing countries; especially for applications requiring fast …

Factors associated with virological non-suppression among HIV-positive patients on antiretroviral therapy in Uganda, August 2014–July 2015

L Bulage, I Ssewanyana, V Nankabirwa… - BMC infectious …, 2017 - Springer
Background Despite the growing number of people on antiretroviral therapy (ART), there is
limited information about virological non-suppression and its determinants among HIV …

Limited emergence of resistance to integrase strand transfer inhibitors (INSTIs) in ART-experienced participants failing dolutegravir-based antiretroviral therapy: A …

A Abdullahi, IM Kida, UA Maina… - Journal of …, 2023 - academic.oup.com
Background Due to the high prevalence of resistance to NNRTI-based ART since 2018,
consolidated recommendations from the WHO have indicated dolutegravir as the preferred …

Global epidemiology of drug resistance after failure of WHO recommended first-line regimens for adult HIV-1 infection: a multicentre retrospective cohort study

J Gregson, M Tang, N Ndembi, RL Hamers… - The Lancet infectious …, 2016 - thelancet.com
Background Antiretroviral therapy (ART) is crucial for controlling HIV-1 infection through
wide-scale treatment as prevention and pre-exposure prophylaxis (PrEP). Potent tenofovir …

Antiretroviral treatment of adult HIV infection: 2010 recommendations of the International AIDS Society–USA panel

MA Thompson, JA Aberg, P Cahn, JSG Montaner… - Jama, 2010 - jamanetwork.com
Context Recent data regarding the consequences of untreated human immunodeficiency
virus (HIV) infection and the expansion of treatment choices for antiretroviral-naive and …

Global trends in antiretroviral resistance in treatment-naive individuals with HIV after rollout of antiretroviral treatment in resource-limited settings: a global …

RK Gupta, MR Jordan, BJ Sultan, A Hill, DHJ Davis… - The Lancet, 2012 - thelancet.com
Background The emergence and spread of high levels of HIV-1 drug resistance in resource-
limited settings where combination antiretroviral treatment has been scaled up could …

Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: a review of the last 20 years (1989 …

MP de Béthune - Antiviral research, 2010 - Elsevier
It is almost 20 years since NNRTIs were identified as a new class of antiretroviral drugs for
the treatment of HIV-1 infection. Although they belong to different and diverse chemical …

Virological follow-up of adult patients in antiretroviral treatment programmes in sub-Saharan Africa: a systematic review

RE Barth, MFS van der Loeff, R Schuurman… - The Lancet infectious …, 2010 - thelancet.com
Following large-scale roll-out of antiretroviral therapy in sub-Saharan Africa, the non-clinical
efficacy of antiretroviral therapy has received little attention. We aimed to systematically …