Fungal infections represent a major, albeit neglected, public health threat with serious
medical and economic burdens globally. With unacceptably high mortality rates, invasive …

Candidiasis is a fungal infection caused by Candida spp. especially Candida albicans, C.
glabrata, C. parapsilosis and C. tropicalis. Although the medicinal therapeutic strategies …

Life-threatening systemic infections often occur due to the translocation of pathogens across
the gut barrier and into the bloodstream. While the microbial and host mechanisms …

Vulvovaginal candidiasis (VVC), caused primarily by the human fungal pathogen Candida
albicans, results in significant quality-of-life issues for women worldwide. Candidalysin, a …

Candidalysin is the first cytolytic peptide toxin identified in any human fungal pathogen.
Candidalysin is secreted by Candida albicans and is critical for driving infection and host …

Candida albicans is the principal causative agent of lethal fungal infections, predominantly
in immunocompromised hosts. Extracellular vesicles (EVs) have been described as crucial …

Candida albicans is a common opportunistic fungal pathogen that causes a wide range of
infections from superficial mucosal to hematogenously disseminated candidiasis. The …

Host released alarmins and antimicrobial peptides (AMPs) are highly effective as antifungal
agents and inducers. Whilst some are expressed constitutively at mucosal tissues, the …

Albumin is abundant in serum but is also excreted at mucosal surfaces and enters tissues
when inflammation increases vascular permeability. Host-associated opportunistic …

Fungal resistance against frequently used antifungal medicines used for invasive
candidiasis and other fungal infections is directing scientist for searching and developing …