Skeletal muscle energy metabolism during exercise

M Hargreaves, LL Spriet - Nature metabolism, 2020 - nature.com
The continual supply of ATP to the fundamental cellular processes that underpin skeletal
muscle contraction during exercise is essential for sports performance in events lasting …

Exogenous ketone supplements in athletic contexts: past, present, and future

M Evans, TS McClure, AP Koutnik, B Egan - Sports medicine, 2022 - Springer
The ketone bodies acetoacetate (AcAc) and β-hydroxybutyrate (βHB) have pleiotropic
effects in multiple organs including brain, heart, and skeletal muscle by serving as an …

Crisis of confidence averted: Impairment of exercise economy and performance in elite race walkers by ketogenic low carbohydrate, high fat (LCHF) diet is …

LM Burke, AP Sharma, IA Heikura, SF Forbes… - PloS one, 2020 - journals.plos.org
Introduction We repeated our study of intensified training on a ketogenic low-carbohydrate
(CHO), high-fat diet (LCHF) in world-class endurance athletes, with further investigation of a …

Efficacy of popular diets applied by endurance athletes on sports performance: Beneficial or detrimental? A narrative review

A Devrim-Lanpir, L Hill, B Knechtle - Nutrients, 2021 - mdpi.com
Endurance athletes need a regular and well-detailed nutrition program in order to fill their
energy stores before training/racing, to provide nutritional support that will allow them to …

[HTML][HTML] Effects of exogenous ketone supplementation on blood glucose: a systematic review and meta-analysis

K Falkenhain, A Daraei, SC Forbes, JP Little - Advances in Nutrition, 2022 - Elsevier
Recently developed ketone (monoester or salt) supplements acutely elevate blood β-
hydroxybutyrate (BHB) exogenously without prolonged periods of fasting or carbohydrate …

[HTML][HTML] Utility of ketone supplementation to enhance physical performance: a systematic review

LM Margolis, KS O'Fallon - Advances in Nutrition, 2020 - Elsevier
Ingesting exogenous ketone bodies has been touted as producing ergogenic effects by
altering substrate metabolism; however, research findings from recent studies appear …

[HTML][HTML] The effect of blood ketone concentration and exercise intensity on exogenous ketone oxidation rates in athletes

DJ Dearlove, OK Harrison, L Hodson… - Medicine and science …, 2021 - ncbi.nlm.nih.gov
Methods Six athletes completed cycling ergometer exercise on three occasions within a
single-blind, random-order controlled, crossover design study. Exercise duration was 60 …

Exogenous ketosis impacts neither performance nor muscle glycogen breakdown in prolonged endurance exercise

C Poffé, M Ramaekers, S Bogaerts… - Journal of applied …, 2020 - journals.physiology.org
Available evidence indicates that ketone bodies inhibit glycolysis in contracting muscles.
Therefore, we investigated whether acute exogenous ketosis by oral ketone ester (KE) …

[HTML][HTML] Ketogenic diets and Ketone suplementation: A strategy for therapeutic intervention

CGJ Saris, S Timmers - Frontiers in nutrition, 2022 - frontiersin.org
Ketogenic diets and orally administered exogenous ketone supplements are strategies to
increase serum ketone bodies serving as an alternative energy fuel for high energy …

[HTML][HTML] Bicarbonate unlocks the ergogenic action of ketone monoester intake in endurance exercise

C Poffé, M Ramaekers, S Bogaerts… - Medicine and Science in …, 2021 - ncbi.nlm.nih.gov
Purpose We recently reported that oral ketone ester (KE) intake before and during the initial
30 min of a 3 h 15 min simulated cycling race (RACE) transiently decreased blood pH and …