[HTML][HTML] PCSK9 and cancer: Rethinking the link

K Mahboobnia, M Pirro, E Marini, F Grignani… - Biomedicine & …, 2021 - Elsevier
Background Cancer is emerging as a major problem globally, as it accounts for the second
cause of death despite medical advances. According to epidemiological and basic studies …

[HTML][HTML] Frontiers of MicroRNA signature in non-small cell lung cancer

X Zhu, M Kudo, X Huang, H Sui, H Tian… - Frontiers in Cell and …, 2021 - frontiersin.org
Lung cancer is the leading cause of cancer-related deaths worldwide and non-small cell
lung cancer (NSCLC) accounts for more than 80% of all lung cancer cases. Recent …

[HTML][HTML] The emerging role of the KCTD proteins in cancer

A Angrisani, A Di Fiore, E De Smaele… - Cell Communication and …, 2021 - Springer
The human family of Potassium (K+) Channel Tetramerization Domain (KCTD) proteins
counts 25 members, and a significant number of them are still only partially characterized …

[HTML][HTML] Hypoxia-inducible microRNA-224 promotes the cell growth, migration and invasion by directly targeting RASSF8 in gastric cancer

C He, L Wang, J Zhang, H Xu - Molecular cancer, 2017 - Springer
Background Hypoxia plays an important role in the development of various cancers.
MicroRNAs (miRNAs) act as post-transcriptional regulators of gene expression and …

MicroRNA and ER stress in cancer

T Kim, CM Croce - Seminars in cancer biology, 2021 - Elsevier
The development of biological technologies in genomics, proteomics, and bioinformatics
has led to the identification and characterization of the complete set of coding genes and …

[HTML][HTML] LncRNA-TUSC7/miR-224 affected chemotherapy resistance of esophageal squamous cell carcinoma by competitively regulating DESC1

Z Chang, Y Jia, W Zhang, L Song, M Gao, M Li… - Journal of Experimental …, 2018 - Springer
Background This study aims to clarify the underlying mechanism for the tumor suppressive
function of lnc TUSC7 in chemotherapy resistance of esophageal squamous cell carcinoma …

Role of miRNA in lung cancer-potential biomarkers and therapies

X Du, J Zhang, J Wang, X Lin… - Current pharmaceutical …, 2017 - ingentaconnect.com
MicroRNAs (miRNAs) are small noncoding RNAs, which downregulate gene expression by
repressing or degrading mRNA targets. Lung cancer (LC), together with liver and colorectal …

[HTML][HTML] miR-224 aggravates cancer-associated fibroblast-induced progression of non-small cell lung cancer by modulating a positive loop of the SIRT3/AMPK/mTOR …

J Zhang, L Han, J Yu, H Li, Q Li - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Objectives: Cancer-associated fibroblast (CAF) is among the most important tumor-host
microenvironment components by affecting tumor progression. This study explored the role …

[HTML][HTML] MiR-122 targets SerpinB3 and is involved in sorafenib resistance in hepatocellular carcinoma

C Turato, F Fornari, D Pollutri, M Fassan… - Journal of clinical …, 2019 - mdpi.com
The only first-line treatment approved for advanced hepatocellular carcinoma (HCC) is
sorafenib. Since many patients experience drug resistance, the discovery of more effective …

[HTML][HTML] Investigating melanogenesis-related microRNAs as disease biomarkers in vitiligo

HY Abdallah, NR Abdelhamid, EA Mohammed… - Scientific Reports, 2022 - nature.com
Vitiligo is considered a disabling disease that affects physical, social, psychological, and
occupational aspects of an individual's quality of life. The search for non-invasive and …