Utilisation of dietary carbohydrates in farmed fishes: new insights on influencing factors, biological limitations and future strategies

BS Kamalam, F Medale, S Panserat - Aquaculture, 2017 - Elsevier
Carbohydrates are the most abundant class of energy yielding nutrients which is
economically indispensable in commercial fish feed formulations. But, the ability of farmed …

Metformin environmental exposure: A systematic review

EP Ambrosio-Albuquerque, LF Cusioli… - Environmental …, 2021 - Elsevier
This review discussed the occurrence, ecological impacts, and effects of metformin, a drug
used for type 2 diabetes among other diseases. It is one of the most commonly found …

Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells

Z Yang, H Fujii, SV Mohan, JJ Goronzy… - Journal of Experimental …, 2013 - rupress.org
In the HLA class II–associated autoimmune syndrome rheumatoid arthritis (RA), CD4 T cells
are critical drivers of pathogenic immunity. We have explored the metabolic activity of RA T …

Identification of anti-diabetes peptides from Spirulina platensis

S Hu, X Fan, P Qi, X Zhang - Journal of functional foods, 2019 - Elsevier
In this study, ultrasound coupled with subcritical water (USW) technology was employed to
extract S. platensis protein, and its inhibitory effect on three enzymes (α-amylase, α …

Insulin signaling pathway assessment by enhancing antioxidant activity due to morin using in vitro rat skeletal muscle L6 myotubes cells

PK Issac, R Karan, A Guru, R Pachaiappan… - Molecular Biology …, 2021 - Springer
Background Plant-derived phytochemicals such as flavonoids have been explored to be
powerful antioxidants that protect against oxidative stress-related diseases. In the present …

[HTML][HTML] Mitochondrial fatty acid β-oxidation inhibition promotes glucose utilization and protein deposition through energy homeostasis remodeling in fish

LY Li, JM Li, LJ Ning, DL Lu, Y Luo, Q Ma… - The Journal of …, 2020 - Elsevier
Background: Fish cannot use carbohydrate efficiently and instead utilize protein for energy
supply, thus limiting dietary protein storage. Protein deposition is dependent on protein …

Deteriorating insulin resistance due to WL15 peptide from cysteine and glycine‐rich protein 2 in high glucose‐induced rat skeletal muscle L6 cells

A Guru, PK Issac, NT Saraswathi… - Cell Biology …, 2021 - Wiley Online Library
This study investigates the antioxidant and antidiabetic activity of the WL15 peptide derived
from Channa striatus on regulating the antioxidant property in the rat skeletal muscle cell …

Molecular process of glucose uptake and glycogen storage due to hamamelitannin via insulin signalling cascade in glucose metabolism

PK Issac, A Guru, SS Chandrakumar, C Lite… - Molecular Biology …, 2020 - Springer
Understanding the mechanism by which the exogenous biomolecule modulates the GLUT-4
signalling cascade along with the information on glucose metabolism is essential for finding …

Interactions between dietary carbohydrate and metformin: implications on energy sensing, insulin signaling pathway, glycolipid metabolism and glucose tolerance in …

C Xu, WB Liu, DD Zhang, XF Cao, HJ Shi, XF Li - Aquaculture, 2018 - Elsevier
A 12-week feeding trial was performed to evaluate the effects of metformin on growth
performance, energy sensing, insulin signaling pathway, glycolipid metabolism and glucose …

[HTML][HTML] Energy metabolism disorders and potential therapeutic drugs in heart failure

Y He, W Huang, C Zhang, L Chen, R Xu, N Li… - … Pharmaceutica Sinica B, 2021 - Elsevier
Heart failure (HF) is a global public health problem with high morbidity and mortality. A large
number of studies have shown that HF is caused by severe energy metabolism disorders …