The minimal structural unit of a solid tumor is a single cell or a cellular compartment such as
the nucleus. A closer look inside the cells reveals that there are functional compartments or …

Collagen is the major fibrillar protein in most living organisms. Among the different types of
collagen, type I collagen is the most abundant one in tissues of marine invertebrates. Due to …

The tumour stroma, and in particular the extracellular matrix (ECM), is a salient feature of
solid tumours that plays a crucial role in shaping their progression. Many desmoplastic …

The tumour stroma regulates nearly all stages of carcinogenesis. Stromal heterogeneity in
human triple‐negative breast cancers (TNBCs) remains poorly understood, limiting the …

The lysyl oxidase family represents a promising target in stromal targeting of solid tumors
due to the importance of this family in crosslinking and stabilizing fibrillar collagens and its …

The incidence of hepatocellular carcinoma (HCC) is rapidly rising largely because of
increased obesity leading to nonalcoholic steatohepatitis (NASH), a known HCC risk factor …

Heterogeneous subtypes of cancer-associated fibroblasts (CAFs) coexist within pancreatic
cancer tissues and can both promote and restrain disease progression. Here, we interrogate …

Cancer-associated fibroblasts (CAF) are major contributors to pancreatic ductal
adenocarcinoma (PDAC) progression through protumor signaling and the generation of …

The world fisheries resources have exceeded 160 million tons in recent years. However,
every year a considerable amount of total catch is discarded as by-catch or as processing …

The biosynthesis, structural diversity, and functionality of collagens of sponge origin are still
paradigms and causes of scientific controversy. This review has the ambitious goal of …