Targeting the gut microbiota for cancer therapy

MR Fernandes, P Aggarwal, RGF Costa… - Nature Reviews …, 2022 - nature.com
Growing evidence suggests that the gut microbiota modulates the efficacy and toxicity of
cancer therapy, most notably immunotherapy and its immune-related adverse effects. The …

[HTML][HTML] Understanding the impact of antibiotic perturbation on the human microbiome

DJ Schwartz, AE Langdon, G Dantas - Genome medicine, 2020 - Springer
The human gut microbiome is a dynamic collection of bacteria, archaea, fungi, and viruses
that performs essential functions for immune development, pathogen colonization …

[HTML][HTML] An omics-based framework for assessing the health risk of antimicrobial resistance genes

AN Zhang, JM Gaston, CL Dai, S Zhao, M Poyet… - Nature …, 2021 - nature.com
Antibiotic resistance genes (ARGs) are widespread among bacteria. However, not all ARGs
pose serious threats to public health, highlighting the importance of identifying those that are …

Role of the gut microbiota in nutrition and health

AM Valdes, J Walter, E Segal, TD Spector - Bmj, 2018 - bmj.com
Role of the gut microbiota in nutrition and health Page 1 36 BMJ 361:Supp1 | the bmj Science
and PoliticS of nutrition Role of the gut microbiota in nutrition and health Ana M Valdes and …

Microbiota as predictor of mortality in allogeneic hematopoietic-cell transplantation

JU Peled, ALC Gomes, SM Devlin… - … England Journal of …, 2020 - Mass Medical Soc
Background Relationships between microbiota composition and clinical outcomes after
allogeneic hematopoietic-cell transplantation have been described in single-center studies …

[HTML][HTML] Drug-Resistant E. coli Bacteremia Transmitted by Fecal Microbiota Transplant

Z DeFilipp, PP Bloom, M Torres Soto… - … England Journal of …, 2019 - Mass Medical Soc
Fecal microbiota transplantation (FMT) is an emerging therapy for recurrent or refractory
Clostridioides difficile infection and is being actively investigated for other conditions. We …

Fecal microbiota transplantation promotes reduction of antimicrobial resistance by strain replacement

MH Woodworth, RE Conrad, M Haldopoulos… - Science translational …, 2023 - science.org
Multidrug-resistant organism (MDRO) colonization is a fundamental challenge in
antimicrobial resistance. Limited studies have shown that fecal microbiota transplantation …

[HTML][HTML] Factors affecting the composition of the gut microbiota, and its modulation

N Hasan, H Yang - PeerJ, 2019 - peerj.com
Gut microbiota have important functions in the body, and imbalances in the composition and
diversity of those microbiota can cause several diseases. The host fosters favorable …

[HTML][HTML] The super-donor phenomenon in fecal microbiota transplantation

BC Wilson, T Vatanen, WS Cutfield… - Frontiers in cellular and …, 2019 - frontiersin.org
Fecal microbiota transplantation (FMT) has become a highly effective bacteriotherapy for
recurrent Clostridium difficile infection. Meanwhile the efficacy of FMT for treating chronic …

[HTML][HTML] Introduction to host microbiome symbiosis in health and disease

F Malard, J Dore, B Gaugler, M Mohty - Mucosal Immunology, 2021 - Elsevier
Humans share a core intestinal microbiome and yet human microbiome differs by genes,
species, enterotypes (ecology), and gene count (microbial diversity). Achievement of …