Lead toxicity and potential therapeutic effect of plant-derived polyphenols
C Niu, M Dong, Y Niu - Phytomedicine, 2023 - Elsevier
Background Due to its unique physical and chemical properties, lead is still used worldwide
in several applications, especially in industry. Both environmental and industrial lead …
in several applications, especially in industry. Both environmental and industrial lead …
Direct effects of toxic divalent cations on contractile proteins with implications for the heart: unraveling mechanisms of dysfunction
OP Gerzen, VO Votinova, IK Potoskueva… - International Journal of …, 2023 - mdpi.com
The binding of calcium and magnesium ions to proteins is crucial for regulating heart
contraction. However, other divalent cations, including xenobiotics, can accumulate in the …
contraction. However, other divalent cations, including xenobiotics, can accumulate in the …
Elevated inflammatory Lp-PLA2 and IL-6 link e-waste Pb toxicity to cardiovascular risk factors in preschool children
X Lu, X Xu, Y Zhang, Y Zhang, C Wang, X Huo - Environmental pollution, 2018 - Elsevier
Cardiovascular toxicity of lead (Pb) manifests primarily as an effect on blood pressure and
eventual increased risk of atherosclerosis and cardiovascular events. Therefore, we …
eventual increased risk of atherosclerosis and cardiovascular events. Therefore, we …
Co-exposure subacute toxicity of silica nanoparticles and lead acetate on cardiovascular system
L Feng, X Yang, Y Shi, S Liang, T Zhao… - International journal …, 2018 - Taylor & Francis
Background The harmful effects following the release of nanomaterials into environment are
of great concern today. Purpose In this study, subacute effect due to co-exposure to low …
of great concern today. Purpose In this study, subacute effect due to co-exposure to low …
Chronic lead exposure increases blood pressure and myocardial contractility in rats
M Fioresi, MR Simoes, LB Furieri, GB Broseghini-Filho… - PloS one, 2014 - journals.plos.org
We investigated the cardiovascular effects of lead exposure, emphasising its direct action on
myocardial contractility. Male Wistar rats were sorted randomly into two groups: control (Ct) …
myocardial contractility. Male Wistar rats were sorted randomly into two groups: control (Ct) …
Molecular mechanisms of mechanical function changes of the rat myocardium under subchronic lead exposure
OP Gerzen, SR Nabiev, SV Klinova… - Food and Chemical …, 2022 - Elsevier
A moderate degree of lead intoxication was observed in male rats after repeated
intraperitoneal injections with two doses of lead acetate three times a week during 5 (12.5 …
intraperitoneal injections with two doses of lead acetate three times a week during 5 (12.5 …
Low-level chronic lead exposure impairs neural control of blood pressure and heart rate in rats
MR Simoes, SC Preti, BF Azevedo, J Fiorim… - Cardiovascular …, 2017 - Springer
Lead (Pb) induces adverse effects when it chronically accumulates in the body, including
effects on the nervous and cardiovascular systems. Wistar rats were exposed to lead acetate …
effects on the nervous and cardiovascular systems. Wistar rats were exposed to lead acetate …
Dose dependency of subchronic lead acetate exposure on biophysical characteristics of rats' right atrium and ventricle
AA Balakin, IA Minigalieva, DA Kuznetsov… - The European Physical …, 2024 - Springer
The study investigated the dose-dependent effects of lead acetate on the atrial and
ventricular myocardium, as well as on hematological parameters in young male rats under …
ventricular myocardium, as well as on hematological parameters in young male rats under …
Further verification of some postulates of the combined toxicity theory: New animal experimental data on separate and joint adverse effects of lead and cadmium
SV Klinova, IA Minigalieva, LI Privalova… - Food and Chemical …, 2020 - Elsevier
Outbred male rats were repeatedly injected intraperitoneally two-level sub-lethal doses of
lead acetate and/or cadmium chloride solutions 3 times a week during 6 weeks. The animals …
lead acetate and/or cadmium chloride solutions 3 times a week during 6 weeks. The animals …
Effects of subchronic lead intoxication of rats on the myocardium contractility
YL Protsenko, BA Katsnelson, SV Klinova… - Food and chemical …, 2018 - Elsevier
Outbred male rats were repeatedly injected IP with sub-lethal doses of lead acetate 3 times
a week during 5 weeks. They developed an explicit, even if moderate, lead intoxication …
a week during 5 weeks. They developed an explicit, even if moderate, lead intoxication …